从的根中分离得到的阿瑞洛他姆生物碱。

Aristololactam alkaloids from the roots of .

机构信息

Key Laboratory of Tropical Medicinal Resourse Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, Hainan, China.

Key Laboratory of Medicinal and Edible Plants Resources of Hainan Province, Hainan Institute of Science and Technology, Haikou, Hainan, China.

出版信息

Nat Prod Res. 2021 Apr;35(7):1084-1089. doi: 10.1080/14786419.2019.1638384. Epub 2019 Jul 9.

DOI:10.1080/14786419.2019.1638384

PMID:31286798

Abstract

A novel aristololactam alkaloid, dasymalactam A (), together with nine known analogues (), were isolated from the roots of . Their structures were elucidated by IR, NMR and MS spectrums and comparisons with data reported in the literature. All compounds demonstrated weak cytotoxicity against Hela, MCF-7, A-549, MGC-803, and COLO-205 human cancer cell lines.

摘要

一种新型的阿朴菲类生物碱，dasymalactam A ()，与 9 种已知类似物 () 一起从的根部分离得到。它们的结构通过 IR、NMR 和 MS 光谱解析，并与文献报道的数据进行比较来确定。所有化合物对 Hela、MCF-7、A-549、MGC-803 和 COLO-205 人癌细胞系均显示出较弱的细胞毒性。