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一种新型靶向线粒体的一氧化碳特异性荧光探针，用于活细胞成像检测。

A new mitochondrion targetable fluorescent probe for carbon monoxide-specific detection and live cell imaging.

机构信息

College of Pharmacy, College of Nursing, Shandong Engineering Research Center for Smart Materials and Regenerative Medicine, Weifang Medical University, Weifang 261053, China.

出版信息

Chem Commun (Camb). 2019 Aug 7;55(64):9444-9447. doi: 10.1039/c9cc03909k.

DOI:10.1039/c9cc03909k
PMID:31287465
Abstract

A new mitochondrion targetable molecular probe for carbon monoxide (CO)-specific detection based on palladium-free mediated opening of spirolactam was designed. The turn-on red fluorescence caused by CO enables a safe and powerful method for unravelling the function of CO in biological systems to be established.

摘要

设计了一种基于无钯介导螺环内酰胺开环的新型线粒体靶向一氧化碳（CO）特异性检测分子探针。CO 引起的开环红荧光为揭示 CO 在生物系统中的功能提供了一种安全而强大的方法。

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