人乳头瘤病毒基因型在尖锐湿疣中的分布：一项奥地利队列研究。
Distribution of Human Papillomavirus Genotypes in Condylomata Acuminata: An Austrian Cohort Study.
机构信息
Department of Dermatology, Kepler University Hospital, Linz, Austria.
Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
出版信息
Dermatology. 2019;235(5):413-417. doi: 10.1159/000500908. Epub 2019 Jul 9.
INTRODUCTION
Condylomata acuminata are caused by various genotypes of human papilloma viruses (HPV).
METHODS
We assessed the frequency of 33 different HPV DNA types in 49 patients with condylomata acuminata by the polymerase chain reaction technique.
RESULTS
Forty-two percent of the patients were infected with low-risk genotypes, and 21% of the patients tested positive for high-risk genotypes. Multiple infections with low- and high-risk genotypes were detectable in 36% of the patients.
CONCLUSION
As our results are in line with previous large-scale reports, our data might serve as a basis for monitoring the efficacy of HPV vaccination in Austria.
简介
尖锐湿疣是由多种人乳头瘤病毒（HPV）基因型引起的。
方法
我们通过聚合酶链反应技术在 49 例尖锐湿疣患者中评估了 33 种不同 HPV DNA 类型的频率。
结果
42%的患者感染了低危型基因型，21%的患者检测出高危型基因型阳性。36%的患者可检测到低危和高危基因型的混合感染。
结论
由于我们的结果与之前的大规模报告一致，因此我们的数据可以为监测 HPV 疫苗在奥地利的疗效提供依据。
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