Cao Huihua, Xie Jun, Qian Yongxiang, Wu Yugang, Tang Zhaoqing
Department of General Surgery, The Third Affiliated Hospital of Soochow University and The First People's Hospital of Changzhou, Changzhou, Jiangsu 213000, P.R. China.
Department of Pathology, The Third Affiliated Hospital of Soochow University and The First People's Hospital of Changzhou, Changzhou, Jiangsu 213000, P.R. China.
Oncol Lett. 2019 Jul;18(1):545-552. doi: 10.3892/ol.2019.10368. Epub 2019 May 17.
Lymphoepithelioma-like gastric carcinoma (LELGC) is a rare type of gastric cancer characterized by intense lymphocytic infiltration of the stroma. LELGC is associated with Epstein-Barr virus infection and has a favorable prognosis compared with other types of gastric carcinoma. The clinical symptoms of LELGC are usually similar to those of conventional gastric carcinoma. The diagnosis of LELGC is established based on pathological, histological and immunohistochemical findings. The present report describes the cases of two patients with LELGC who underwent esophagogastroduodenoscopy and computed tomography scans prior to surgery. The two patients accepted surgical treatment, and postoperative pathological and immunohistochemical analyses confirmed LELGC. Neither patient experienced local recurrence or distant metastasis during the postoperative period.
淋巴上皮瘤样胃癌(LELGC)是一种罕见的胃癌类型,其特征是基质中有大量淋巴细胞浸润。LELGC与爱泼斯坦-巴尔病毒感染有关,与其他类型的胃癌相比预后较好。LELGC的临床症状通常与传统胃癌相似。LELGC的诊断基于病理、组织学和免疫组化结果。本报告描述了两名LELGC患者的病例,他们在手术前接受了食管胃十二指肠镜检查和计算机断层扫描。两名患者均接受了手术治疗,术后病理和免疫组化分析证实为LELGC。两名患者在术后均未出现局部复发或远处转移。