Goh S W, Adawiyah J, Md Nor N, Yap Fbb, Ch'ng Pwb, Chang C C
MB BCh (Soton), MRCP (UK) Medical Department, University Kebangsaan Malaysia Medical Centre, Kuala Lumpur Malaysia., Email:
MB BCh BAO, MMed (UKM) AdvMDerm (UKM), University Kebangsaan Malaysia Medical Centre, Kuala Lumpur Malaysia., Email:
Malays Fam Physician. 2019 Apr 30;14(1):42-46. eCollection 2019.
Prurigo pigmentosa is an inflammatory dermatosis characterized by a pruritic, symmetrically distributed erythematous papular or papulo-vesicular eruption on the trunk arranged in a reticulated pattern that resolves with hyperpigmentation. It is typically non-responsive to topical or systemic steroid therapy. The exact etiology is unknown, but it is more commonly described in the Far East countries. Dietary change is one of the predisposing factors. We report on nine young adult patients with prurigo pigmentosa, among whom five were on ketogenic diets prior to the onset of the eruptions. All cases resolved with oral doxycycline with no recurrence. We hope to improve the awareness of this uncommon skin condition among general practitioners and physicians so that disfiguring hyperpigmentation due to delayed diagnosis and treatment can be avoided.
色素性痒疹是一种炎症性皮肤病，其特征为躯干上出现瘙痒性、对称分布的红斑丘疹或丘疱疹，呈网状排列，消退后会出现色素沉着。它通常对局部或全身类固醇治疗无反应。确切病因尚不清楚，但在远东国家更为常见。饮食变化是诱发因素之一。我们报告了9例色素性痒疹的年轻成年患者，其中5例在皮疹发作前采用生酮饮食。所有病例口服多西环素后均痊愈，无复发。我们希望提高全科医生和内科医生对这种罕见皮肤病的认识，以便避免因诊断和治疗延迟而导致的毁容性色素沉着。
