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多节段腰椎管狭窄症采用 Dynesys 稳定与腰椎融合治疗老年患者:至少 5 年随访的回顾性研究。

Multi-segmental lumbar spinal stenosis treated with Dynesys stabilization versus lumbar fusion in elderly patients: a retrospective study with a minimum of 5 years' follow-up.

机构信息

Department of Orthopeadic Surgery, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, People's Republic of China.

出版信息

Arch Orthop Trauma Surg. 2019 Oct;139(10):1361-1368. doi: 10.1007/s00402-019-03234-3. Epub 2019 Jul 9.

Abstract

INTRODUCTION

Middle- and long-term outcomes of multi-segmental lumbar spinal stenosis treated with Dynesys stabilization (DS) have rarely been reported. Older age and multi-segmental degeneration may be positive factors in achieving satisfactory outcomes following DS. The present study aimed to compare the middle- and long-term outcomes of DS with lumbar fusion for treatment of multi-segmental lumbar spinal stenosis (ms-LSS) in elderly patients.

MATERIALS AND METHODS

This study retrospectively analyzed patients with ms-LSS treated by DS or lumbar fusion from January 2011 to April 2013. Twenty-two patients were included in the Dynesys group, and 44 patients treated by lumbar fusion and rigid fixation were included in the fusion group. Clinical outcomes were assessed by VAS and ODI. Radiological outcomes were measured by range of motion (ROM) of stabilized segments and the proximal adjacent segment, intervertebral disc height (DH) and L1-S1 lumbar lordosis angle (LL). Modified Pfirrmann grade score was used to access disc degeneration.

OUTCOMES

The mean follow-up time of the Dynesys group and fusion group was 68.50 ± 6.40 and 70.14 ± 7.26 months, respectively. Baseline data were similar between the two groups. There were no significant differences between the two groups in terms of improvement of clinical outcomes (VAS and ODI). DS preserved a certain degree of ROM (3.74 ± 2.00) of surgical segments. ROM of proximal adjacent segment underwent an increase in both groups at the final follow-up. The DH of the surgical segments and proximal adjacent segment in both groups was significantly lower than that before surgery (P = 0.000). LL of both groups improved (P = 0.000), and there was no significant difference between the two groups. The modified Pfirrmann score of proximal adjacent segment of both groups increased at the final follow-up. The fusion group underwent a more significant increase (P = 0.000), whereas the inter-group difference showed no significance (P = 0.090).

CONCLUSION

DS is a safe and effective surgical treatment of multi-segmental lumbar spinal stenosis in the elderly population. DS preserves a certain degree of mobility of surgical segments.

摘要

简介

Dynesys 稳定系统(DS)治疗多节段腰椎管狭窄症的中长期疗效鲜有报道。年龄较大和多节段退变可能是 DS 治疗后获得满意疗效的积极因素。本研究旨在比较 DS 与腰椎融合治疗老年多节段腰椎管狭窄症(ms-LSS)的中长期疗效。

材料与方法

回顾性分析 2011 年 1 月至 2013 年 4 月采用 DS 或腰椎融合治疗 ms-LSS 的患者。Dynesys 组 22 例,腰椎融合加刚性固定组 44 例。采用视觉模拟评分(VAS)和 Oswestry 功能障碍指数(ODI)评估临床疗效。通过稳定节段和近端邻接节段的活动度(ROM)、椎间盘高度(DH)和 L1-S1 腰椎前凸角(LL)测量影像学结果。采用改良 Pfirrmann 分级评价椎间盘退变。

结果

Dynesys 组和融合组的平均随访时间分别为 68.50±6.40 和 70.14±7.26 个月。两组基线数据无统计学差异。两组临床疗效(VAS 和 ODI)改善程度无统计学差异。DS 保留了一定程度的手术节段 ROM(3.74±2.00)。两组近端邻接节段的 ROM 在末次随访时均增加。两组手术节段和近端邻接节段的 DH 均明显低于术前(P=0.000)。两组 LL 均改善(P=0.000),组间无统计学差异。两组近端邻接节段改良 Pfirrmann 评分在末次随访时均增加。融合组增加更显著(P=0.000),但组间差异无统计学意义(P=0.090)。

结论

DS 是治疗老年多节段腰椎管狭窄症的一种安全有效的手术方法。DS 能在一定程度上保留手术节段的活动度。

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