• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

The locus coeruleus: Another vulnerability target in Parkinson's disease.

作者信息

Oertel Wolfgang H, Henrich Martin T, Janzen Annette, Geibl Fanni F

机构信息

Department of Neurology, Philipps University Marburg, Marburg, Germany.

出版信息

Mov Disord. 2019 Oct;34(10):1423-1429. doi: 10.1002/mds.27785. Epub 2019 Jul 10.

DOI:10.1002/mds.27785
PMID:31291485
Abstract
摘要

相似文献

1
The locus coeruleus: Another vulnerability target in Parkinson's disease.蓝斑:帕金森病的另一个易损靶点。
Mov Disord. 2019 Oct;34(10):1423-1429. doi: 10.1002/mds.27785. Epub 2019 Jul 10.
2
The role of the locus coeruleus in the development of Parkinson's disease.蓝斑在帕金森病发展过程中的作用。
Neurosci Biobehav Rev. 2000 Aug;24(6):655-68. doi: 10.1016/s0149-7634(00)00028-2.
3
Ubiquitin expression in globose tangles in the locus coeruleus in brains of patients with Alzheimer's and Parkinson's diseases.阿尔茨海默病和帕金森病患者大脑中蓝斑核球形缠结中的泛素表达。
Neurosci Lett. 1992 Feb 17;136(1):59-62. doi: 10.1016/0304-3940(92)90647-p.
4
A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson's disease-like pathology in neurons and glia.A53T-α-突触核蛋白在小鼠蓝斑中的过表达诱导神经元和神经胶质细胞出现类似帕金森病的病变。
Acta Neuropathol Commun. 2018 May 10;6(1):39. doi: 10.1186/s40478-018-0541-1.
5
Parkinson's disease and dementia: norepinephrine and dopamine in locus ceruleus.帕金森病与痴呆:蓝斑中的去甲肾上腺素和多巴胺
Neurology. 1987 Jan;37(1):42-6. doi: 10.1212/wnl.37.1.42.
6
The functional anatomy of noradrenergic neurons in Parkinson's disease.帕金森病中去甲肾上腺素能神经元的功能解剖学
Funct Neurol. 1999 Apr-Jun;14(2):97-109.
7
Behavioral and neurochemical effects of noradrenergic depletions with N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine in 6-hydroxydopamine-induced rat model of Parkinson's disease.在6-羟基多巴胺诱导的帕金森病大鼠模型中,N-(2-氯乙基)-N-乙基-2-溴苄胺去甲肾上腺素能耗竭的行为和神经化学效应。
Behav Brain Res. 2004 May 5;151(1-2):191-9. doi: 10.1016/j.bbr.2003.08.016.
8
Extrahypothalamic vasopressin is unchanged in Parkinson's disease and Huntington's disease.下丘脑外加压素在帕金森病和亨廷顿病中无变化。
Brain Res. 1982 Dec 16;253(1-2):341-3. doi: 10.1016/0006-8993(82)90706-5.
9
Possible role of neuromelanin in the pathogenesis of Parkinson's disease.神经黑色素在帕金森病发病机制中的可能作用。
Mech Ageing Dev. 1983 Feb;21(2):193-203. doi: 10.1016/0047-6374(83)90074-x.
10
The locus coeruleus and dopaminergic function in rat brain: implications to parkinsonism.大鼠脑中的蓝斑与多巴胺能功能:对帕金森病的影响
Brain Res Bull. 1992 May;28(5):663-6. doi: 10.1016/0361-9230(92)90244-r.

引用本文的文献

1
Neuropathological examination of 12 cases of familial Parkinson's disease with LRRK2 I2020T mutation including tau and TDP-43 pathology.对12例携带LRRK2 I2020T突变的家族性帕金森病患者进行神经病理学检查,包括tau蛋白和TDP - 43病理学检查。
J Neurol. 2025 Jun 9;272(7):450. doi: 10.1007/s00415-025-13148-3.
2
Fading Blue: Exploring the Causes of Locus Coeruleus Damage Across the Lifespan.渐失的蓝色:探索蓝斑在整个生命周期中受损的原因
Antioxidants (Basel). 2025 Feb 22;14(3):255. doi: 10.3390/antiox14030255.
3
Individual-specific metabolic network based on F-FDG PET revealing multi-level aberrant metabolisms in Parkinson's disease.
基于 F-FDG PET 的个体特异性代谢网络揭示帕金森病的多层次代谢异常。
Hum Brain Mapp. 2024 Oct;45(14):e70026. doi: 10.1002/hbm.70026.
4
Bibliometric analysis of global research trends in magnetic resonance imaging studies of substantia nigra in Parkinson's disease (2001-2024).帕金森病黑质磁共振成像研究全球研究趋势的文献计量分析(2001 - 2024年)
Front Aging Neurosci. 2024 Sep 3;16:1455562. doi: 10.3389/fnagi.2024.1455562. eCollection 2024.
5
External stimulation of the trigeminal nerve causes pupil dilation in healthy volunteers, suggesting locus coeruleus modulation.对健康志愿者的三叉神经进行外部刺激会导致瞳孔扩张,这表明蓝斑存在调节作用。
Brain Stimul. 2024 May-Jun;17(3):678-680. doi: 10.1016/j.brs.2024.05.008. Epub 2024 May 17.
6
Long-Term Impact of Diffuse Traumatic Brain Injury on Neuroinflammation and Catecholaminergic Signaling: Potential Relevance for Parkinson's Disease Risk.弥漫性创伤性脑损伤对神经炎症和儿茶酚胺能信号的长期影响:对帕金森病风险的潜在相关性。
Molecules. 2024 Mar 26;29(7):1470. doi: 10.3390/molecules29071470.
7
Metabolic energy decline coupled dysregulation of catecholamine metabolism in physiologically highly active neurons: implications for selective neuronal death in Parkinson's disease.代谢能量下降与生理上高度活跃神经元中儿茶酚胺代谢的失调相关联:对帕金森病中选择性神经元死亡的影响。
Front Aging Neurosci. 2024 Feb 21;16:1339295. doi: 10.3389/fnagi.2024.1339295. eCollection 2024.
8
Grid cells: the missing link in understanding Parkinson's disease?网格细胞:理解帕金森病的缺失环节?
Front Neurosci. 2024 Feb 8;18:1276714. doi: 10.3389/fnins.2024.1276714. eCollection 2024.
9
New insights in animal models of neurotoxicity-induced neurodegeneration.神经毒性诱导神经退行性变动物模型的新见解。
Front Neurosci. 2024 Jan 8;17:1248727. doi: 10.3389/fnins.2023.1248727. eCollection 2023.
10
Neurogenic orthostatic hypotension in Parkinson's disease: is there a role for locus coeruleus magnetic resonance imaging?帕金森病所致的神经源性直立性低血压:蓝斑磁共振成像是否有作用?
J Neural Transm (Vienna). 2024 Feb;131(2):157-164. doi: 10.1007/s00702-023-02721-7. Epub 2023 Nov 30.