Jiang Mei, Deng Xu, Qiu Zixiong, Li Jie, Song Zifan, Chen Xiaoshuai, Chen Ruiqi, Huang Xianzhi, Cui Xiaojun, Fu Yuan
Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, Department of Human Anatomy, Dongguan Campus, Guangdong Medical University, Dongguan, China.
School of Sports Health, Guangdong Vocational Institute of Sport, Guangzhou, China.
Front Aging Neurosci. 2024 Sep 3;16:1455562. doi: 10.3389/fnagi.2024.1455562. eCollection 2024.
Parkinson's disease (PD) is a globally prevalent neurodegenerative disorder, primarily characterized by muscle rigidity, resting tremor, and bradykinesia. The incidence of PD is rapidly escalating worldwide. Numerous studies have been conducted on the application of magnetic resonance imaging (MRI) in investigating the substantia nigra (SN) in PD patients. However, to date, no bibliometric analysis has been performed on this specific research area. Therefore, this study aimed to provide a comprehensive analysis of the current status in MRI research on the SN in PD patients.
MRI study records related to the SN in PD patients from 2001 to 2024 were searched by using the Web of Science Core Collection (WOSCC) database and then the CiteSpace and VOSviewer were used to conduct bibliometric analysis.
Our analysis found that the number of published articles related studies on MRI of the SN in PD showed an overall upward trend over the past decade, in which Lehericy, Stephane, Du, Guangwei, and Huang, Xuemei are the top three authors with the most articles. Additionally, United States, China and Germany are the main contributors to MRI studies of SN in PD. And Shanghai Jiao Tong University, University of Florida and Seoul National University are the leading institutions in the field. Finally, the keyword analysis showed that the hotspots and trends of research in this field are mainly concentrated in quantitative susceptibility mapping, neuroimaging, and neuromelanin-sensitive MRI.
These analysis identified the most influential authors, institutions, countries and research hotspots in the field of SN-MRI research in PD, which has reference significance for the research interest in this field and provides a new idea for PD prevention.
帕金森病（PD）是一种全球流行的神经退行性疾病，主要特征为肌肉僵硬、静止性震颤和运动迟缓。PD的发病率在全球范围内迅速上升。关于磁共振成像（MRI）在PD患者黑质（SN）研究中的应用，已经开展了大量研究。然而，迄今为止，尚未对这一特定研究领域进行文献计量分析。因此，本研究旨在全面分析PD患者SN的MRI研究现状。
利用科学引文索引核心合集（WOSCC）数据库检索2001年至2024年与PD患者SN相关的MRI研究记录，然后使用CiteSpace和VOSviewer进行文献计量分析。
我们的分析发现，过去十年中，关于PD患者SN的MRI相关研究发表文章数量总体呈上升趋势，其中勒赫里西、斯特凡、杜光伟和黄雪梅是发文量排名前三的作者。此外，美国、中国和德国是PD患者SN的MRI研究的主要贡献国家。上海交通大学、佛罗里达大学和首尔国立大学是该领域的领先机构。最后，关键词分析表明，该领域研究的热点和趋势主要集中在定量磁化率成像、神经影像学和对神经黑色素敏感的MRI。
这些分析确定了PD患者SN-MRI研究领域中最具影响力的作者、机构、国家和研究热点，对该领域的研究兴趣具有参考意义，并为PD预防提供了新思路。
