儿童不可切除复发性恶性骶尾部畸胎瘤的放化疗治疗：病例报告及文献综述
Unresectable recurrence malignant sacrococcygeal teratoma in children treated with chemoradiotherapy: Case report and literature review.
作者信息
Huang Yecai, Feng Mei, Yin Jun, Fu Bingyu, Lang Jinyi
机构信息
Department of Radiation Oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
出版信息
Rep Pract Oncol Radiother. 2019 Jul-Aug;24(4):392-398. doi: 10.1016/j.rpor.2019.06.002. Epub 2019 Jun 22.
Sacrococcygeal teratoma is the most common germ cell neoplasia that consists of tissues derived from primitive germ layers. Approximately 10-20% of patients are malignant. Because of the high rate of recurrence, treatment strategies for malignant sacrococcygeal teratomas are limited. Hence, we report a case of malignant sacrococcygeal teratoma treated with concurrent chemoradiotherapy plus adjuvant chemotherapy and review the literature. This case report indicates that chemoradiation plus adjuvant chemotherapy may be a treatment option for malignant SCT which is not technically resectable or with residual lesion after surgery.
骶尾部畸胎瘤是最常见的生殖细胞肿瘤，由源自原始胚层的组织构成。约10%-20%的患者为恶性。由于复发率高，恶性骶尾部畸胎瘤的治疗策略有限。因此，我们报告1例采用同步放化疗加辅助化疗治疗的恶性骶尾部畸胎瘤病例并复习文献。本病例报告表明，放化疗加辅助化疗可能是无法进行手术切除或术后有残留病灶的恶性骶尾部畸胎瘤的一种治疗选择。
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