Kutsumi H, Inaoka T, Ohnishi K
Department of Parasitology, Asahikawa Medical College, Japan.
Hokkaido Igaku Zasshi. 1988 Jan;63(1):80-4.
Chinese hamsters (Cricetulus griseus Milne-Edwards: CHA colony) were experimentally infected with Schistosoma japonicum cercariae by the percutaneous route and intraperitoneal inoculation to confirm their susceptibility to the infection with this parasite in comparison with that of mice (DD). Chinese hamsters proved to be highly susceptible to percutaneous and intraperitoneal infection with S. japonicum. The eggs of S. japonicum were recognized in feces of all Chinese hamsters and mice from about 6 weeks after infection. The mortality within 50 weeks post-infection was lower in Chinese hamsters than in mice. Eight out of 18 Chinese hamsters survived more than 50 weeks post-infection, seven of these showed eggs in their feces beyond this period, whereas no fecal eggs was detected in the same period in the five mice which survived more than 50 weeks post-infection. Chinese hamsters seem to be equally susceptible as mice to S. japonicum infection and more tolerant than mice to the worm load.
将中国仓鼠(黑线仓鼠:CHA 品系)通过经皮途径和腹腔接种的方式用日本血吸虫尾蚴进行实验性感染,以确认其与小鼠(DD 品系)相比对这种寄生虫感染的易感性。结果证明,中国仓鼠对日本血吸虫的经皮和腹腔感染高度易感。在感染后约 6 周,在所有中国仓鼠和小鼠的粪便中都发现了日本血吸虫卵。感染后 50 周内中国仓鼠的死亡率低于小鼠。18 只中国仓鼠中有 8 只在感染后存活超过 50 周,其中 7 只在此期间粪便中仍有虫卵,而在感染后存活超过 50 周的 5 只小鼠中,同期未检测到粪便虫卵。中国仓鼠似乎与小鼠对日本血吸虫感染的易感性相同,但比小鼠对虫负荷的耐受性更强。