Black A J, Wilson T S
Department of Medical Microbiology, Belfast City Hospital, Northern Ireland.
J Clin Pathol. 1988 Mar;41(3):329-33. doi: 10.1136/jcp.41.3.329.
Over 12 months serum was collected from 45 inpatients, with acute bronchopulmonary infection, in whose sputum Branhamella catarrhalis predominated, or was the sole pathogen. Serum was examined for IgG against B catarrhalis using an immunofluorescence antibody test. Acute and convalescent sera were compared with sera of age and sex matched controls. The convalescent sera had significantly higher titres than the acute sera which in turn had higher titres than the controls. The findings confirm the role of B catarrhalis as a respiratory pathogen and suggest that patients with chronic pulmonary disease are more prone to infection with this organism than the general population.
在12个月的时间里,从45例急性支气管肺部感染的住院患者中采集血清,这些患者的痰液中卡他布兰汉菌占主导地位或为唯一病原体。使用免疫荧光抗体试验检测血清中针对卡他布兰汉菌的IgG。将急性期和恢复期血清与年龄和性别匹配的对照组血清进行比较。恢复期血清的滴度明显高于急性期血清,而急性期血清的滴度又高于对照组。这些发现证实了卡他布兰汉菌作为呼吸道病原体的作用,并表明慢性肺病患者比普通人群更容易感染这种微生物。