印度乙肝疫苗首针：是时候重新考虑了。
Hepatitis B vaccine birth dose in India: time to reconsider.
机构信息
All India Institute of Medical Sciences, Raipur, India.
出版信息
Hum Vaccin Immunother. 2020;16(1):158-160. doi: 10.1080/21645515.2019.1640557. Epub 2019 Sep 13.
Abstract
Viral hepatitis is increasingly being recognized as a public health problem in India with 96% of all hepatitis mortality attributed to hepatitis B and C combined. It has been recognized that hepatitis B vaccination has resulted in substantial reductions in the incidence of acute and chronic hepatitis B infections and carriage. Although coverage of third-dose hepatitis B vaccine has reached 86%, the birth-dose coverage was only 45% in 2015 despite high rates of institutional deliveries (79%). With the target set at 90% coverage of birth-dose hepatitis B vaccine by 2030, it is imperative to immediately incorporate WHO/SAGE recommendations of administering the hepatitis B vaccine birth dose until 7 d into the National Immunization Schedule (NIS).
摘要
病毒性肝炎在印度日益被视为一个公共卫生问题，所有肝炎死亡病例中有 96%归因于乙型肝炎和丙型肝炎合并感染。乙型肝炎疫苗接种已被证实可显著降低急性和慢性乙型肝炎感染和携带的发生率。尽管第三剂乙型肝炎疫苗的覆盖率已达到 86%，但 2015 年出生时第一剂的覆盖率仅为 45%，尽管机构分娩率很高（79%）。目标是到 2030 年将乙型肝炎疫苗出生时第一剂的覆盖率提高到 90%，因此必须立即将世界卫生组织/免疫战略咨询专家组关于在国家免疫计划（NIS）中实施乙型肝炎疫苗出生时第一剂的建议纳入其中。
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