Faculty of Psychology, Southwest University, Chongqing, China.
Key Research Base of Humanities and Social Sciences of the Ministry of Education, Academy of Psychology and Behavior, Tianjin Normal University, Tianjin, China; Faculty of Psychology, Tianjin Normal University, Tianjin, China; Center of Collaborative Innovation for Assessment and Promotion of Mental Health, Tianjin, China.
Neuroimage. 2019 Oct 15;200:556-561. doi: 10.1016/j.neuroimage.2019.07.015. Epub 2019 Jul 8.
Intertemporal choice refers to the process of making decisions by weighing short- and long-term benefits and costs. On average people prefer immediate rewards over delayed rewards with larger amounts, which is a form of decision impulsivity. Based on previous research showing the importance of the dorsal medial prefrontal cortex (DMPFC) in decision impulsivity, the present study examined whether regional homogeneity (ReHo) patterns in DMPFC were associated with individual differences in intertemporal choices. Two cohorts of college students (N = 239 and N = 227, respectively) were recruited and resting-state data were collected. Results from both univariate and multivariate pattern analyses of the two cohorts consistently showed that ReHo patterns in the DMPFC were associated with the delay discounting rate (i.e., log k). These results further support the important role of DMPFC in intertemporal choice and have potential practical implications for decision making in our daily life and at the level of national policies as well as for the treatment of clinical populations with decision impulsivity (e.g., gamblers, individuals with substance use disorders).
跨期选择是指通过权衡短期和长期收益与成本来做出决策的过程。一般来说，人们更喜欢即时奖励而不是延迟奖励，而且奖励越大，这种情况就越明显，这是一种决策冲动的形式。基于先前的研究表明背内侧前额叶皮层（DMPFC）在决策冲动中的重要性，本研究探讨了 DMPFC 中的局部一致性（ReHo）模式是否与跨期选择的个体差异有关。招募了两个大学生队列（分别为 N=239 和 N=227，并采集了静息态数据。两个队列的单变量和多变量模式分析结果一致表明，DMPFC 的 ReHo 模式与延迟折扣率（即 log k）有关。这些结果进一步支持了 DMPFC 在跨期选择中的重要作用，对于我们日常生活中的决策以及国家政策层面的决策具有潜在的实际意义，同时也为治疗具有决策冲动的临床人群（如赌徒、物质使用障碍患者）提供了帮助。
