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人源ST398型甲氧西林敏感金黄色葡萄球菌中度毒力菌株GD1108的全基因组序列

Complete Genome Sequence of GD1108, a Moderate-Virulence Strain of Human-Associated ST398 Methicillin-Susceptible Staphylococcus aureus.

作者信息

McClure Jo-Ann, Shideler Steven M, Zhang Kunyan

机构信息

Centre for Antimicrobial Resistance, Alberta Health Services/Alberta Public Laboratories/University of Calgary, Calgary, Alberta, Canada.

Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada.

出版信息

Microbiol Resour Announc. 2019 Jul 11;8(28):e00687-19. doi: 10.1128/MRA.00687-19.

DOI:10.1128/MRA.00687-19
PMID:31296689
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6624772/
Abstract

multilocus sequence type 398 (ST398) is responsible for an increasing number of severe infections in humans. There are no reports detailing if all ST398 strains are equally virulent. We present the genome sequence of the moderate-virulence ST398 methicillin-susceptible strain GD1108, determined in a infection model, to reveal the ST398 sublineage virulence.

摘要

多位点序列类型398（ST398）导致人类中越来越多的严重感染。目前尚无报告详细说明所有ST398菌株的毒力是否相同。我们展示了在感染模型中测定的中等毒力的ST398甲氧西林敏感菌株GD1108的基因组序列，以揭示ST398亚系的毒力。