Institute for Disease Modeling, Bellevue, WA 98005, USA.
Science. 2019 Jul 12;365(6449). doi: 10.1126/science.aax5552.
Mina (Reports, 8 May 2015, p. 694) used population-level statistical analysis to argue that measles infection results in a 2- to 3-year immunomodulation, implicating measles in substantially more child mortality than previously thought. We show, using both simulation and data from Iceland, that the statistical approach used may be confounded by the 2-year periodicity of measles incidence in the areas studied.
Mina(报道,2015 年 5 月 8 日,第 694 页)利用人群水平的统计分析来论证麻疹感染会导致 2 至 3 年的免疫调节,这意味着麻疹导致的儿童死亡率比之前认为的要高得多。我们利用模拟和冰岛的数据表明,所使用的统计方法可能会受到研究地区麻疹发病率两年周期性的干扰。