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皮肤镜检查在甲黑素沉着症诊断中的重要性

The Importance of Dermatoscopy for the Diagnosis of Melanonychia.

作者信息

Ianoși S L, Calbureanu-Popescu M X, Ianoși N G, Ungureanu Mohora I, Tutunaru C V, Neagoe C D

机构信息

Medical Center Dr. Ianosi, Department of Dermatology, University of Medicine and Pharmacy of Craiova, Romania.

University of Craiova, Department of Applied Mechanics, Craiova, Romania.

出版信息

Curr Health Sci J. 2019 Jan-Mar;45(1):36-41. doi: 10.12865/CHSJ.45.01.04. Epub 2019 Mar 31.

Abstract

UNLABELLED

Melanonychia is the brown or black color of the finger or toe nail due to melanin deposition or melanocytes in the nail plate. The evidence of melanocytic disease is made by the dermatoscope, which allows to highlight the anomalies of the plate. The purpose of our study was to evaluate dermatoscopically the melanonychia, both in the form of stain and longitudinal on finger and/or toe nails in order to establish the type of nail hyperpigmentation.

MATERIALS AND METHOD

33 patients with longitudinal and stain melanonychia were examined with 30x Molemax HD computerized dermatoscope between May 2017-septembre 2018 in this prospective study conducted in the Department of Dermatology of Medical Center Dr. Ianosi (Craiova, Romania). Clinical data included: type of melanonychia, number and name of involved fingers, the presence or absence of fungal infections, nail apparatus tumors or hemorrhage.

RESULTS

The most frequent nail diagnosis was fungal infection (onychomycosis) observed in 18 patients (54.54%), malignant melanoma was diagnosed in 1 patient (3.03%) and the junctional nevus in 4 patients (12.12%). In 18 patients which has longitudinal melanonychia, the most frequent involved finger was the big toe, and in 15 patients which has stain melanonychia, all of them (100%) had affected the big toe, 7 (46.66%) patients had affected the thumb and the same percent the forth finger.

CONCLUSION

Nail dermatoscopy is an important method in establishing the diagnosis of melanonychia and allowed to avoid unnecessary biopsy for melanonychia.

摘要

未标注

甲黑素沉着是指甲板中由于黑色素沉积或黑素细胞导致手指或脚趾甲出现棕色或黑色。皮肤镜可提供黑素细胞疾病的证据,它能够突出显示甲板的异常情况。我们研究的目的是通过皮肤镜评估甲黑素沉着,包括手指和/或脚趾甲上的色斑和纵向甲黑素沉着,以确定指甲色素沉着过度的类型。

材料与方法

在罗马尼亚克拉约瓦伊亚诺西医疗中心皮肤科进行的这项前瞻性研究中,于2017年5月至2018年9月期间,使用30倍的Molemax HD电脑皮肤镜对33例有纵向和色斑状甲黑素沉着的患者进行了检查。临床数据包括:甲黑素沉着的类型、受累手指的数量和名称、是否存在真菌感染、甲器肿瘤或出血。

结果

最常见的指甲诊断是真菌感染(甲癣),18例患者(54.54%)出现该情况,1例患者(3.03%)被诊断为恶性黑色素瘤,4例患者(12.12%)被诊断为交界痣。在18例有纵向甲黑素沉着的患者中,最常受累的手指是大脚趾;在15例有色斑状甲黑素沉着的患者中,所有患者(100%)的大脚趾均受累,7例(46.66%)患者的拇指受累,无名指受累的比例相同。

结论

指甲皮肤镜检查是确立甲黑素沉着诊断的重要方法,可避免对甲黑素沉着进行不必要的活检。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6242/6592664/dc409ad009c1/CHSJ-45-01-36-fig1.jpg

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