Colin M, Avon P
Hôpital de Treichville, Abidjan, Côte d'Ivoire.
Pharmatherapeutica. 1988;5(3):198-203.
Ninety-eight patients suffering from skin and soft tissue infections in the Côte d'Ivoire were treated topically with a new antibiotic, mupirocine, or with placebo in a double-blind study. Patients were allocated at random to receive one or other treatment, applying the ointment, supplied in identical tubes and of similar colour base, to the lesions 3 times a day for 5 days. Overall evaluation of clinical response to treatment showed that the results with mupirocine were significantly superior to those with placebo. No unwanted effects of treatment were observed in either treatment group.
在一项双盲研究中，98名患有皮肤和软组织感染的科特迪瓦患者分别局部使用一种新型抗生素莫匹罗星或安慰剂进行治疗。患者被随机分配接受其中一种治疗，将装在相同管子中、具有相似色素基质的药膏每天3次涂抹于病灶处，持续5天。对治疗临床反应的总体评估表明，使用莫匹罗星的治疗结果显著优于使用安慰剂的结果。两个治疗组均未观察到治疗的不良影响。
