Universidad Central de Venezuela, Caracas, Venezuela.
Cleveland Clinic, Cleveland, OH, USA.
Obes Surg. 2019 Dec;29(12):3987-3991. doi: 10.1007/s11695-019-04071-4.
Obesity in the world has been increasing, and the number of diabetic patients will increase by 114%, and the best treatment results are achieved through surgery. Several techniques have been described; the gastric bypass of an anastomosis (MGB/OAGB) has been gaining popularity for its simplicity and good results. We present a prospective study with this technique in 16 mild obesity patients with type 2 diabetes mellitus or peripheral insulin resistance.
To evaluate weight loss as well as metabolic changes by measuring fasting glycemia and Hb A1c after 1 year of follow-up.
Sixteen patients were operated on with the OAGB/MGB technique from September 2014 to January 2016, with some form of metabolic syndrome, whether DM2, RPI, HBP, or dyslipidemia, including patients in the study with a follow-up of at least 12 months.
There were 13 cases of female sex and 3 of male, average age of 42.9 years, with an average weight of 87.7 kg and BMI of 32.2 kg/m. Metabolic values were fasting glycemia of 193.6 ± 52.9 mg/dl and HbA1c of 8.4% ± 1 (preop) and glycemia posop, 78.8 ± 7.6 mg/dl; HbA1c posop, 6.1 ± 0.2; preop weight, 87.7 ± 14 kg (69-116); weight posop, 66.8 ± 10.5 kg (49-90); BMI preop, 32.2 ± 1.8 (30-34.9); BMI posop, 25.4 ± 1.7 (21.7-27.6); percentage of excess weight lost, 87.6 ± 11.8 (70.9-100) % with 100% remission of diabetes.
The results show the benefits of MGB/OAGB in mild obese diabetic patients.
全球肥胖人数不断增加，糖尿病患者人数将增加 114%，而手术是最佳的治疗手段。目前已经有多种技术被描述，其中胃旁路吻合术（MGB/OAGB）因其操作简单和良好的效果而受到青睐。我们对 16 例 2 型糖尿病或外周胰岛素抵抗的轻度肥胖患者进行了前瞻性研究。
通过测量术后 1 年的空腹血糖和糖化血红蛋白（HbA1c）评估体重减轻和代谢变化。
2014 年 9 月至 2016 年 1 月，16 例患者接受 OAGB/MGB 手术，均患有某种形式的代谢综合征，包括 2 型糖尿病、胰岛素抵抗、高血压或血脂异常，所有患者的随访时间至少为 12 个月。
其中女性 13 例，男性 3 例，平均年龄 42.9 岁，平均体重 87.7kg，BMI 为 32.2kg/m。代谢值为空腹血糖 193.6±52.9mg/dl，糖化血红蛋白 8.4%±1（术前），术后血糖 78.8±7.6mg/dl，糖化血红蛋白 6.1±0.2；术前体重 87.7±14kg（69-116），术后体重 66.8±10.5kg（49-90），BMI 术前 32.2±1.8（30-34.9），术后 25.4±1.7（21.7-27.6），体重减轻百分比为 87.6±11.8%（70.9-100）%，糖尿病完全缓解率为 100%。
结果表明 MGB/OAGB 对轻度肥胖糖尿病患者有益。
