Department of Surgery, Division of Minimally Invasive and Bariatric Surgery, Rasool-e Akram (Hazrat-e Rasool) University Hospital, School of Medicine, Iran University of Medical Sciences, Mansouri St., Niyayesh St., Sattarkhan Ave., Tehran, Iran.
Center of Excellence of European Branch of International Federation for Surgery of Obesity, Rasool-e Akram (Hazrat-e Rasool) University Hospital, Tehran, Iran.
Surg Endosc. 2024 Jul;38(7):3940-3947. doi: 10.1007/s00464-024-10928-2. Epub 2024 Jun 6.
One-anastomosis gastric bypass (OAGB) is gaining more attention in patients with severe obesity and recently is used for patients with body mass index (BMI) < 35 kg/m. In this 5-year single center experience we aim to report our outcomes of using OAGB for patients with BMI < 35 kg/m.
This is a retrospective analysis of prospectively collected data recorded in to our national obesity registry database. Variables including age, sex, weight, BMI, any associated disease, blood levels of metabolic markers, nutrients, and vitamins before and after surgery were extracted and analyzed.
173 patients with mean age and BMI of 41 ± 10 years and 33 ± 1 kg/m underwent OAGB and at least one of the obesity-associated medical problems was found in 88 (50.5%) of them preoperatively. The mean duration of surgery and length of hospital stay were 60.7 ± 7.4 min and 1.3 ± 1.4 days. 78% and 70% of patients had available data at 24 and 60 months, respectively. The mean BMI was 23.9 ± 2.2 kg/m 1 year after surgery and each year after that till 5 years was 24 ± 2, 24.4 ± 2.6, 25.1 ± 2.7, and 25.5 ± 2.7 kg/m. Significant improvement in levels of fasting blood glucose, lipid profile, and liver enzymes were observed.
OAGB for BMI < 35 kg/m has significant effects in weight loss, helps remit diabetes and hypertension in the majority of cases, improves lipid profile, and has no increased burden of postoperative problems or deficiency in nutritional factors rather than what is known and predictable.
单吻合口胃旁路术（OAGB）在重度肥胖患者中越来越受到关注，最近也用于体重指数（BMI）<35kg/m 的患者。在这项为期 5 年的单中心经验中，我们旨在报告使用 OAGB 治疗 BMI<35kg/m 的患者的结果。
这是对前瞻性收集的数据进行的回顾性分析，记录在我们的国家肥胖症注册数据库中。提取并分析了包括年龄、性别、体重、BMI、任何相关疾病、手术前后代谢标志物、营养素和维生素的血液水平在内的变量。
173 名平均年龄和 BMI 为 41±10 岁和 33±1kg/m 的患者接受了 OAGB 治疗，其中 88 名（50.5%）患者术前至少有一种肥胖相关的医学问题。手术的平均持续时间和住院时间分别为 60.7±7.4 分钟和 1.3±1.4 天。78%和 70%的患者在 24 和 60 个月时有可用数据。术后 1 年 BMI 为 23.9±2.2kg/m，此后每年分别为 24±2、24.4±2.6、25.1±2.7 和 25.5±2.7kg/m。空腹血糖、血脂谱和肝酶水平显著改善。
对于 BMI<35kg/m 的 OAGB 具有显著的减肥效果，有助于缓解大多数情况下的糖尿病和高血压，改善血脂谱，并且术后问题或营养因素缺乏的负担没有增加，这与已知和可预测的情况不同。
