Instituto de Laparoscopia Avanzada del Sureste (INLAPSUR).
Nutr Hosp. 2021 Oct 13;38(5):971-977. doi: 10.20960/nh.03545.
Introduction: type-2 diabetes mellitus (DM2) is a major health problem, as it leads to increased morbidity and mortality. Metabolic surgery has shown good results in glycemic control; however, its use has not become popular. Objectives: to evaluate DM2 remission, as well as changes in body mass index (BMI), in overweight diabetic patients after undergoing metabolic surgery. Methods: a retrospective review was carried out of all patients with DM2 and BMI between 25 and 29.9 kg/m2 who underwent laparoscopic one-anastomosis gastric bypass (OAGB) as metabolic procedure between 2016 and 2019. Results: a total of 15 patients were included with a mean age of 46.6 ± 11.25 years. Mean BMI was 28.41 ± 0.94 kg/m2. Average duration was 5.4 ± 2.79 years, and presurgical fasting glucose was 288.53 ± 65.22 mg/dL. Preoperative glycated hemoglobin (HbA1c) was 9.58 ± 1.66 %. Two years after surgery HbA1c was 5.21 ± 0.26 %. The remission rate of DM2 was 100 %. All patients maintained a normal BMI range. Conclusions: OAGB is a valid alternative for complete DM2 remission no matter if it is not accompanied by some degree of obesity, since in this case the length of the biliopancreatic limb and common channel is modified to make a less malabsorptive procedure.
2 型糖尿病（DM2）是一个主要的健康问题，因为它会导致发病率和死亡率的增加。代谢手术在血糖控制方面显示出良好的效果；然而，其应用并没有普及。目的：评估超重糖尿病患者接受代谢手术后 DM2 的缓解情况，以及体重指数（BMI）的变化。方法：对 2016 年至 2019 年间接受腹腔镜单吻合胃旁路术（OAGB）作为代谢手术的 25 至 29.9 kg/m2 之间的 DM2 和 BMI 的所有患者进行回顾性分析。结果：共纳入 15 例患者，平均年龄为 46.6 ± 11.25 岁。平均 BMI 为 28.41 ± 0.94 kg/m2。平均病程为 5.4 ± 2.79 年，术前空腹血糖为 288.53 ± 65.22mg/dL。术前糖化血红蛋白（HbA1c）为 9.58 ± 1.66%。术后 2 年 HbA1c 为 5.21 ± 0.26%。DM2 的缓解率为 100%。所有患者均维持正常 BMI 范围。结论：OAGB 是完全缓解 DM2 的有效替代方法，无论其是否伴有一定程度的肥胖，因为在这种情况下，胆胰支和共同通道的长度会改变，使手术的吸收不良程度降低。
Zotero 插件