Tobacco Research and Treatment Center, Division of General Internal Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA.
Department of Medicine, Harvard Medical School, Boston, MA.
Nicotine Tob Res. 2020 Apr 21;22(5):728-733. doi: 10.1093/ntr/ntz114.
Electronic cigarettes (e-cigarettes) could benefit public health if they help current smokers to stop smoking long term, but evidence that they do so is limited. We aimed to determine the association between e-cigarette use and subsequent smoking cessation in a nationally representative cohort of US smokers followed for 2 years.
We analyzed data from adult cigarette smokers in Waves 1 through 3 of the Population Assessment of Tobacco and Health study. The primary exposure was e-cigarette use at Wave 1. The primary outcome was prolonged cigarette abstinence, defined as past 30-day cigarette abstinence at Waves 2 and 3 (1- and 2-year follow-up).
Among Wave 1 cigarette smokers, 3.6% were current daily e-cigarette users, 18% were current non-daily e-cigarette users, and 78% reported no current e-cigarette use. In multivariable-adjusted analyses, daily e-cigarette use at Wave 1 was associated with higher odds of prolonged cigarette smoking abstinence at Waves 2 and 3 compared to nonuse of e-cigarettes (11% vs. 6%, adjusted odds ratio [AOR] = 1.77, 95% confidence interval [CI] = 1.08 to 2.89). Non-daily e-cigarette use was not associated with prolonged cigarette smoking abstinence. Among Wave 1 daily e-cigarette users who were abstinent from cigarette smoking at Wave 3, 63% were using e-cigarettes at Wave 3.
In this longitudinal cohort study of US adult cigarette smokers, daily but not non-daily e-cigarette use was associated with higher odds of prolonged cigarette smoking abstinence over 2 years, compared to no e-cigarette use. Daily use of e-cigarettes may help some smokers to stop smoking combustible cigarettes.
In this nationally representative longitudinal cohort study of US adult cigarette smokers, daily e-cigarette use, compared to no e-cigarette use, was associated with a 77% increased odds of prolonged cigarette smoking abstinence over the subsequent 2 years. Regular use of e-cigarettes may help some smokers to stop smoking combustible cigarettes.
如果电子烟能帮助当前吸烟者长期戒烟，从而有益于公共健康，但目前关于电子烟是否能达到这一效果的证据有限。我们旨在确定在一项为期 2 年的美国代表性吸烟者队列研究中，电子烟使用与随后戒烟之间的关联。
我们分析了来自人口烟草健康评估研究第 1 至 3 波的成年香烟吸烟者的数据。主要暴露因素是第 1 波的电子烟使用。主要结果是延长的香烟戒烟，定义为第 2 波和第 3 波（1 年和 2 年随访）过去 30 天的香烟戒烟。
在第 1 波香烟吸烟者中，3.6%是当前每日电子烟使用者，18%是当前非每日电子烟使用者，78%报告没有当前电子烟使用。在多变量调整分析中，与非电子烟使用者相比，第 1 波时的每日电子烟使用与延长的香烟戒烟几率更高（11%与 6%，调整后的优势比[OR] = 1.77，95%置信区间[CI] = 1.08 至 2.89）。非每日电子烟使用与延长的香烟戒烟无关。在第 1 波时已经戒烟的每日电子烟使用者中，有 63%在第 3 波时使用电子烟。
在这项对美国成年香烟吸烟者的纵向队列研究中，与不使用电子烟相比，每日而非非每日电子烟使用与 2 年内延长的香烟戒烟几率更高。与不使用电子烟相比，每日使用电子烟可能会帮助一些吸烟者戒烟。
在这项对美国成年香烟吸烟者的全国代表性纵向队列研究中，与不使用电子烟相比，每日电子烟使用与随后 2 年内延长的香烟戒烟几率增加了 77%。电子烟的常规使用可能有助于一些吸烟者戒烟。
