Department of Psychology, Vanderbilt University, 301 Wilson Hall, 111 21st Avenue South, Nashville, TN 37203, USA.
University of Louisville, USA.
J Affect Disord. 2019 Oct 1;257:45-54. doi: 10.1016/j.jad.2019.06.064. Epub 2019 Jul 2.
Obsessive-compulsive disorder (OCD) is a heterogeneous condition that consists of distinct subtypes, and identification of its core symptoms may inform how to best conceptualize the heterogeneity. Accordingly, we used network analysis to evaluate which symptoms (and associations between symptoms) are most central to OCD symptoms and beliefs.
Participants consisted of a combined sample of adults with a primary diagnosis of OCD (N = 150), those with other primary diagnoses (N = 114), and an unselected nonclinical sample (N = 310). Network analysis was used to identify the most central symptoms (nodes) and associations between symptoms (edges) assessed by the Obsessive-Compulsive Inventory-Revised and the Obsessional Beliefs Questionnaire-44.
The most central symptoms in the network were negative appraisals of intrusive thoughts (i.e., Having intrusive thoughts means I'm out of control). Some of the strongest associations between symptoms were also observed for those pertaining to intrusive thoughts and their negative appraisal. Furthermore, central symptoms in the network predicted depression and anxiety (over and above peripheral symptoms) among those with a primary diagnosis of OCD, but not the severity of OCD symptoms.
The approach was exploratory rather than experimental and relied solely on self-report measures of OCD symptoms and beliefs.
Negative appraisals of intrusive thoughts were the most central symptoms in the OCD network, and they uniquely predict co-occurring symptoms of anxiety and depression, suggesting that these symptoms should be prioritized in theoretical and treatment models of OCD.
强迫症(OCD)是一种异质性疾病,由不同的亚型组成,确定其核心症状可以帮助我们更好地理解其异质性。因此,我们使用网络分析来评估哪些症状(以及症状之间的关联)对 OCD 症状和信念最为重要。
参与者包括一组患有 OCD 主要诊断的成年人(N=150)、其他主要诊断的成年人(N=114)和未选择的非临床样本(N=310)的混合样本。网络分析用于识别由强迫症量表修订版(Obsessive-Compulsive Inventory-Revised)和强迫症信念问卷-44(Obsessional Beliefs Questionnaire-44)评估的最核心症状(节点)和症状之间的关联。
网络中最核心的症状是对侵入性思维的负面评价(即,有侵入性思维意味着我失去了控制)。还观察到一些与侵入性思维及其负面评价相关的最强关联。此外,网络中的核心症状可以预测 OCD 主要诊断者的抑郁和焦虑(超过外周症状),但不能预测 OCD 症状的严重程度。
该方法是探索性的,而不是实验性的,仅依赖于 OCD 症状和信念的自我报告测量。
对侵入性思维的负面评价是 OCD 网络中最核心的症状,它们可以独特地预测焦虑和抑郁的共病症状,这表明这些症状应该在 OCD 的理论和治疗模型中优先考虑。