亚临床抑郁与 2 型糖尿病患者自我护理行为的关系：系统评价观察性研究的方案。
Association between subthreshold depression and self-care behaviour in people with type 2 diabetes: a protocol for systematic review of observational studies.
机构信息
School of Nursing and Midwifery, La Trobe University, Melbourne, Australia.
Nepal Diabetic Society, Kathmandu, Nepal.
出版信息
Syst Rev. 2019 Jul 12;8(1):167. doi: 10.1186/s13643-019-1084-7.
BACKGROUND
Depression is a common comorbidity in type 2 diabetes. Studies have consistently shown that major depression is associated with decreased diabetic self-care behaviour. People with subthreshold depression experience greater functional impairment, have a poorer quality of life and use health services more than those without depressive symptoms. Although subthreshold depression impacts self-care behaviour, the relationship between subthreshold depression and diabetes self-care behaviour has not been systematically reviewed. The objective of this systematic review is to determine the association between subthreshold depression and self-care behaviour in adults with type 2 diabetes.
METHODS
This protocol will follow the guideline of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols 2015 (PRISMA-P-2015). A systematic search of literature will be conducted for observational studies reporting the association between subthreshold depression and self-care behaviour in adults aged 18 years or over and diagnosed with type 2 diabetes. Electronic databases including MEDLINE, EMBASE, PsycINFO, Emcare and CINAHL will be searched using predefined search terms. Title and abstract, full-text screening and data extraction of identified articles will be done by two reviewers independently. Discrepancies will be resolved by a third author. The methodological quality of the included studies will be assessed using The Joanna Briggs Institute (JBI) risk of bias tools. The review results will be presented in the form of narrative synthesis, and if sufficient studies are available and variability among the studies is low, a random effects meta-analysis will be done to quantify the result.
DISCUSSION
This review will synthesise evidence on the association between subthreshold depression and self-care behaviour in type 2 diabetic adults. The findings will be useful to researchers and policymakers to determine the most effective approach to overall diabetes management. The review will also identify research gaps in the current literature and provide direction for future research in this area of study.
SYSTEMATIC REVIEW REGISTRATION
PROSPERO CRD42018116373.
背景
抑郁症是 2 型糖尿病的常见合并症。研究一致表明，重度抑郁症与糖尿病自我护理行为减少有关。患有阈下抑郁症的人比没有抑郁症状的人功能障碍更大，生活质量更差，使用卫生服务更多。尽管阈下抑郁症会影响自我护理行为，但阈下抑郁症与糖尿病自我护理行为之间的关系尚未得到系统审查。本系统评价的目的是确定 2 型糖尿病成人阈下抑郁症与自我护理行为之间的关系。
方法
本方案将遵循 2015 年系统评价和荟萃分析报告规范（PRISMA-P-2015）。将对文献进行系统检索，以查找报告成人（年龄≥ 18 岁） 2 型糖尿病患者阈下抑郁症与自我护理行为之间关联的观察性研究。将使用预定义的搜索词搜索电子数据库，包括 MEDLINE、EMBASE、PsycINFO、Emcare 和 CINAHL。将由两名评审员独立进行标题和摘要、全文筛选和已识别文章的数据提取。如有分歧，将由第三名作者解决。将使用 Joanna Briggs 研究所（JBI）偏倚风险工具评估纳入研究的方法学质量。将以叙述性综合的形式呈现综述结果，如果有足够的研究且研究之间的变异性较低，则将进行随机效应荟萃分析以量化结果。
讨论
本综述将综合关于 2 型糖尿病成人阈下抑郁症与自我护理行为之间关系的证据。研究结果将有助于研究人员和政策制定者确定整体糖尿病管理的最有效方法。该综述还将确定当前文献中的研究空白，并为该研究领域的未来研究提供方向。
系统评价注册
PROSPERO CRD42018116373。
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