Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taiwan.
Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
J Formos Med Assoc. 2019 Nov;118 Suppl 2:S66-S73. doi: 10.1016/j.jfma.2019.06.016. Epub 2019 Jul 9.
BACKGROUND/PURPOSE: Diabetes mellitus (DM) and DM-related complications place a high socioeconomic burden on individuals and society. Updating nationwide information periodically is thus pivotal to preventing DM and improving its management in Taiwan.
We used the National Health Insurance Research Database; disease diagnosis codes were assigned according to the International Classification of Diseases, 9th Revision, Clinical Modification. DM was defined as ≥3 outpatient visits or 1 hospitalization within a year. We excluded individuals with gestational DM, those with missing data, and those aged >100 years. Type 1 DM (T1DM) was defined based on information from the catastrophic illness registry.
From 2005 to 2014, total population with DM increased by 66% and age-standardized prevalence in patients aged 20-79 years increased by 41%. The DM prevalence was generally higher in men; however, the prevalence was higher in women aged ≥65 years. The prevalence of DM was approximately 50% in those aged >80 years. DM incidence increased by 19%; the increase was most obvious in patients aged 20-39 years (p < 0.001). The standardized incidence of T1DM slightly decreased by 11% (p = 0.118) and standardized prevalence of T1DM increased from 0.04% to 0.05%. Number of T1DM accounted for 0.51-0.59% of the entire diabetic population during the observation period.
DM prevalence is continually increasing, but the incidence only marginally increased from 2005 to 2014. Moreover, DM is a major problem in elderly people. The higher incidence of DM in men is consistent with the pandemic of overweight and obesity in men in Taiwan.
背景/目的:糖尿病(DM)及其相关并发症给个人和社会带来了巨大的社会经济负担。因此,定期更新全国范围内的相关信息对于预防 DM 和改善台湾地区的管理至关重要。
我们使用了全民健康保险研究数据库;疾病诊断代码根据国际疾病分类第 9 版临床修订版进行分配。DM 的定义为一年内≥3 次门诊就诊或 1 次住院。我们排除了妊娠糖尿病患者、数据缺失患者以及年龄>100 岁的患者。1 型糖尿病(T1DM)的定义基于灾难性疾病登记处的信息。
从 2005 年到 2014 年,DM 总患者人数增加了 66%,20-79 岁患者的年龄标准化患病率增加了 41%。DM 的患病率通常在男性中较高;然而,≥65 岁的女性中患病率更高。≥80 岁患者的 DM 患病率约为 50%。DM 的发病率增加了 19%;20-39 岁患者的发病率增加最为明显(p<0.001)。T1DM 的标准化发病率略有下降 11%(p=0.118),T1DM 的标准化患病率从 0.04%增加到 0.05%。在观察期间,T1DM 患者人数占全部糖尿病患者的 0.51-0.59%。
DM 的患病率持续增加,但发病率从 2005 年到 2014 年仅略有增加。此外,DM 是老年人的主要问题。男性中 DM 的发病率较高与台湾地区男性超重和肥胖的流行情况一致。