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轻度缺氧缺血性脑病的总 Sarnat 评分可发现具有更高残疾风险的婴儿。

A Total Sarnat Score in Mild Hypoxic-ischemic Encephalopathy Can Detect Infants at Higher Risk of Disability.

机构信息

University of Texas Southwestern Medical Center, Dallas, TX.

University of Texas Southwestern Medical Center, Dallas, TX.

出版信息

J Pediatr. 2019 Nov;214:217-221.e1. doi: 10.1016/j.jpeds.2019.06.026. Epub 2019 Jul 10.

Abstract

To define mild hypoxic-ischemic encephalopathy and distinguish infants at risk of disability in the first 6 hours, this study stratified risk of disability by using early neurologic examination findings of infants enrolled in the Prospective Research for Infants with Mild Encephalopathy cohort. A total Sarnat score of ≥5 when performed at <6 hours of age detected future disability. TRIAL REGISTRATION: Clinicaltrials.gov: NCT01747863.

摘要

为了定义轻度缺氧缺血性脑病并在最初 6 小时内区分有残疾风险的婴儿,本研究通过前瞻性轻度脑病婴儿队列研究中入组婴儿的早期神经检查结果来分层残疾风险。在<6 小时龄时进行的总 Sarnat 评分为≥5 分可预测未来的残疾。

临床试验注册

Clinicaltrials.gov: NCT01747863。

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