酪氨酸酶阳性的眼皮肤白化病基因座与人的β-珠蛋白基因座不连锁。
The tyrosinase-positive oculocutaneous albinism locus is not linked to the beta-globin locus in man.
作者信息
Heim R A, Dunn D S, Candy S E, Zwane E, Kromberg J G, Jenkins T
机构信息
Department of Human Genetics, School of Pathology, South African Institute for Medical Research, Johannesburg.
出版信息
Hum Genet. 1988 May;79(1):89. doi: 10.1007/BF00291719.
PMID:3130302
Abstract
Twenty informative families have been studied. and linkage between the tyrosinase-positive oculocutaneous albinism locus and the beta-globin locus has been excluded with a maximum lod score of -9.85 at 0 = 0.05. In lower mammals there is linkage between the p locus (considered to be equivalent to the human tyrosinase-positive oculocutaneous albinism) and the beta-globin locus.
摘要
已经研究了20个信息丰富的家系。在0 = 0.05时，酪氨酸酶阳性眼皮肤白化病基因座与β-珠蛋白基因座之间的连锁关系已被排除，最大对数优势得分为-9.85。在低等哺乳动物中，p基因座（被认为等同于人类酪氨酸酶阳性眼皮肤白化病）与β-珠蛋白基因座之间存在连锁关系。
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