携带酪氨酸酶阳性眼皮肤白化病基因的黑人携带者的视觉诱发电位
Visual evoked potentials in Negro carriers of the gene for tyrosinase positive oculocutaneous albinism.
作者信息
Castle D, Kromberg J, Kowalsky R, Moosa R, Gillman N, Zwane E, Fritz V
机构信息
Department of Human Genetics, School of Pathology, South African Institute for Medical Research, Johannesburg.
出版信息
J Med Genet. 1988 Dec;25(12):835-7. doi: 10.1136/jmg.25.12.835.
Abstract
Visual evoked potential testing was performed on 15 Negro carriers of the gene for tyrosinase positive oculocutaneous albinism in order to detect whether they have the same visual pathway decussation anomalies as do homozygotes. No subject showed 01-02 asymmetry on monocular testing, indicating that decussation follows the normal pattern. It is concluded that visual evoked potential testing is probably not useful in the detection of Negroes heterozygous for the gene for tyrosinase positive oculocutaneous albinism.
摘要
对15名携带酪氨酸酶阳性眼皮肤白化病基因的黑人携带者进行了视觉诱发电位测试，以检测他们是否具有与纯合子相同的视觉通路交叉异常。在单眼测试中，没有受试者表现出01-02不对称，这表明交叉遵循正常模式。得出的结论是，视觉诱发电位测试可能对检测携带酪氨酸酶阳性眼皮肤白化病基因的黑人杂合子没有用处。
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