Rubinstein A, Ghossein N A, Melamed J, Bosworth J L, Murphy R A
Oncology. 1979;36(1):23-6. doi: 10.1159/000225313.
Various immunological parameters were evaluated in untreated Hodgkin's patients before and after sensitization with dinitrochlorobenzene (DNCB). The ratio (r) of these parameters after/before DNCB sensitization for patients and second/first samples in the controls were calculated. There were significantly more patients in the r greater than 1.1 group for PHA and Con A responses and for peripheral blood T cell percentages. These data suggest that DNCB sensitization may have a nonspecific immunopotentiation effect.
在未经治疗的霍奇金病患者中，在用二硝基氯苯（DNCB）致敏前后评估了各种免疫参数。计算了患者在DNCB致敏后/致敏前这些参数的比值（r）以及对照组中第二次/第一次样本的比值。对于PHA和Con A反应以及外周血T细胞百分比，r大于1.1的组中的患者明显更多。这些数据表明，DNCB致敏可能具有非特异性免疫增强作用。
