New heritable fragile site on chromosome 8 induced by distamycin A.
作者信息
Ochi H, Watanabe S, Yamamoto H
机构信息
Epidemiology Division, National Cancer Center Research Institute, Tokyo.
出版信息
Jpn J Cancer Res. 1988 Feb;79(2):145-7. doi: 10.1111/j.1349-7006.1988.tb01568.x.
Abstract
A possible new heritable fragile site at band 8q24.1, which is known to be a breakpoint in various cancers and contains the c-myc locus, was found in the lymphocytes from a woman with mastopathy. This fragile site was induced by distamycin A treatment, and expressed as gaps and breaks in 18% of the metaphases examined. The lymphocytes from one of her two sons examined also revealed gaps or breaks at the same site of chromosome 8 in 34% of the metaphases. This fragile 8q24.1 band is considered to be a new heritable fragile site induced by distamycin A.
摘要
相似文献
1
New heritable fragile site on chromosome 8 induced by distamycin A.
Jpn J Cancer Res. 1988 Feb;79(2):145-7. doi: 10.1111/j.1349-7006.1988.tb01568.x.
2
Familial fragile site found at the cancer breakpoint (1)(q32). Inducibility by distamycin A, concomitance with fragile (16)(q22).
Hum Genet. 1986 Jul;73(3):232-4. doi: 10.1007/BF00401234.
3
Familial fragility on chromosome 16 (fra 16q22) enhanced by both interferon and Distamycin A.
Hum Genet. 1983;63(4):341-4. doi: 10.1007/BF00274759.
4
The use of distamycin A in human lymphocyte cultures.
Hum Genet. 1984;65(4):377-84. doi: 10.1007/BF00291563.
5
Demonstration of a heritable fragile site in human chromosome 16 with distamycin A.
Cytogenet Cell Genet. 1980;28(1-2):87-94. doi: 10.1159/000131516.
6
Nature of distamycin A-inducible fragile sites.
Cancer Genet Cytogenet. 1988 Sep;34(2):189-94. doi: 10.1016/0165-4608(88)90258-0.
7
A distamycin A-inducible fragile site, FRA8E, located in the region of the hereditary multiple exostoses gene, is not involved in HPV16 DNA integration and amplification.
Cancer Genet Cytogenet. 1998 Feb;101(1):24-34. doi: 10.1016/s0165-4608(97)00222-7.
8
Distamycin A-inducible fragile sites and cancer proneness.
Cancer Genet Cytogenet. 1988 Sep;34(2):177-87. doi: 10.1016/0165-4608(88)90257-9.
9
Enhancement of a fra(16)(q22) with distamycin A: a family ascertained through an abnormal proposita.
Am J Med Genet. 1983 Oct;16(2):277-84. doi: 10.1002/ajmg.1320160216.
10
A new rare heritable fragile site at 8q24.1 found in a Japanese population.
Clin Genet. 1988 Feb;33(2):91-4. doi: 10.1111/j.1399-0004.1988.tb03417.x.
引用本文的文献
1
Induction of distamycin A-inducible rare fragile sites and increased sister chromatid exchanges at the fragile site.
Hum Genet. 1991 Jul;87(3):254-60. doi: 10.1007/BF00200900.
本文引用的文献
1
Demonstration of a heritable fragile site in human chromosome 16 with distamycin A.
Cytogenet Cell Genet. 1980;28(1-2):87-94. doi: 10.1159/000131516.
2
Two human c-onc genes are located on the long arm of chromosome 8.
Proc Natl Acad Sci U S A. 1982 Dec;79(24):7842-6. doi: 10.1073/pnas.79.24.7842.
3
Fragile sites and cancer breakpoints.
Cancer Genet Cytogenet. 1984 Jun;12(2):179-81. doi: 10.1016/0165-4608(84)90132-8.
4
Heritable fragile sites in cancer.
Nature. 1984;308(5960):607-8. doi: 10.1038/308607a0.
5
The chromosomal basis of human neoplasia.
Science. 1983 Jul 15;221(4607):227-36. doi: 10.1126/science.6336310.
6
Expression of cellular myc and mos genes in undifferentiated B cell lymphomas of Burkitt and non-Burkitt types.
Proc Natl Acad Sci U S A. 1983 Apr;80(7):1947-50. doi: 10.1073/pnas.80.7.1947.
7
Report of the Committee on Chromosome Rearrangements in Neoplasia and on Fragile Sites.
Cytogenet Cell Genet. 1985;40(1-4):490-535. doi: 10.1159/000132181.
8
Heritable fragile sites on human chromosomes I. Factors affecting expression in lymphocyte culture.
Am J Hum Genet. 1979 Mar;31(2):125-35.
Zotero 插件