Khan Saima Y
Department of Pediatric and Preventive Dentistry, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Int J Clin Pediatr Dent. 2018 Nov-Dec;11(6):513-518. doi: 10.5005/jp-journals-10005-1567.
Consanguinity is known to alter the population structure but the available literature is almost silent on the association of dental conditions with consanguinity.
The purpose was to assess the various dental developmental anomalies in 6-9 year old children born out of consanguineous and non-consanguineous marriages and its association with their parents.
A cross sectional house-hold survey with a sample size of 2,000 (1,600 non-consanguineous and 400 consanguineous respondents and their parents) using systematic random sampling was planned. Six to nine-year-old children and their parents living in 1,597 households were examined and the information recorded on a pretested self prepared questionnaire. The questionnaire had questions pertaining to personal details, type of consanguineous marriages, history of trauma and examination of dental developmental anomalies.
Multivariate logistic regression showed that non syndromic supernumerary teeth in fathers ( =.009); fusion in mothers ( = 0.002); fusion ( <0.001), nonsyndromic supernumerary teeth ( < 0.001), and microdontia ( = 0.002) in respondents were significantly associated with consanguinity.
A significant association of developmental anomalies in parents with consanguineous marriages and their respondents was observed.
Khan SY. An Exploratory Study of Consanguinity and Dental Developmental Anomalies. Int J Clin Pediatr Dent, 2018;11(6):513-518.
已知近亲结婚会改变人口结构,但现有文献几乎未提及牙齿状况与近亲结婚之间的关联。
旨在评估近亲结婚和非近亲结婚所生育的6至9岁儿童的各种牙齿发育异常情况及其与父母的关系。
计划采用系统随机抽样方法进行一项横断面家庭调查,样本量为2000人(1600名非近亲受访者及其父母和400名近亲受访者及其父母)。对居住在1597户家庭中的6至9岁儿童及其父母进行检查,并将信息记录在预先测试过的自行编制的问卷上。问卷包含有关个人详细信息、近亲结婚类型、创伤史以及牙齿发育异常检查的问题。
多因素逻辑回归显示,父亲的非综合征性多生牙(P = 0.009);母亲的融合牙(P = 0.002);受访者的融合牙(P < 0.001)、非综合征性多生牙(P < 0.001)和过小牙(P = 0.002)与近亲结婚显著相关。
观察到近亲结婚的父母及其子女的发育异常之间存在显著关联。
Khan SY. 近亲结婚与牙齿发育异常的探索性研究。《国际临床儿科牙科学杂志》,2018;11(6):513 - 518。