缅甸CD4细胞计数<100的患者中，在医疗点进行常规即时眼部检查以诊断艾滋病相关巨细胞病毒性视网膜炎
Routine Immediate Eye Examination at the Point of Care for Diagnosis of AIDS-Related Cytomegalovirus Retinitis Among Patients With a CD4 Count <100 in Myanmar.
作者信息
Ei Win Le Shwe Sin, Pyar Soe Kyi, Hilbig Adelene, Murray Jillian, Heiden David
机构信息
MSFCH, Yangon, Myanmar Mission, Myanmar.
MSFCH, Dawei, Myanmar Mission, Myanmar.
出版信息
Open Forum Infect Dis. 2019 Jun 14;6(7):ofz280. doi: 10.1093/ofid/ofz280. eCollection 2019 Jul.
Abstract
A retrospective review of diagnosis of cytomegalovirus retinitis (CMVR) before and after introduction of routine immediate eye examination among AIDS patients in Myanmar with an absolute CD4 T-cell count <100 cells/μL demonstrated an increased detection of CMVR from 1.1% (14/1233) to 10.7% (65/608), an improvement of ~10-fold. Diagnosis of CMVR was achieved a mean of 2 days after clinic enrollment.
摘要
对缅甸艾滋病患者中绝对 CD4 T 细胞计数<100 个细胞/μL 的人群在引入常规即时眼部检查前后巨细胞病毒性视网膜炎（CMVR）的诊断情况进行回顾性分析，结果显示 CMVR 的检出率从 1.1%（14/1233）提高到 10.7%（65/608），提高了约 10 倍。CMVR 的诊断在临床登记后平均 2 天实现。
相似文献
1
Routine Immediate Eye Examination at the Point of Care for Diagnosis of AIDS-Related Cytomegalovirus Retinitis Among Patients With a CD4 Count <100 in Myanmar.
Open Forum Infect Dis. 2019 Jun 14;6(7):ofz280. doi: 10.1093/ofid/ofz280. eCollection 2019 Jul.
2
[Clinical characteristic and treatment of cytomegalovirus retinitis in 80 patients with acquired immunodeficiency syndrome].
Zhonghua Yan Ke Za Zhi. 2014 Mar;50(3):197-202.
3
Utility of Ultra-Wide-Field Imaging for Screening of AIDS-Related Cytomegalovirus Retinitis.
Ophthalmologica. 2021;244(4):334-338. doi: 10.1159/000512634. Epub 2020 Oct 29.
4
Poor predictive value of cytomegalovirus (CMV)-specific T cell assays for the development of CMV retinitis in patients with AIDS.
Clin Infect Dis. 2008 Feb 1;46(3):458-66. doi: 10.1086/525853.
5
Protective immunity to cytomegalovirus (CMV) retinitis in AIDS is associated with CMV-specific T cells that express interferon- gamma and interleukin-2 and have a CD8+ cell early maturational phenotype.
J Infect Dis. 2006 Dec 1;194(11):1537-46. doi: 10.1086/508997. Epub 2006 Oct 26.
6
Cytomegalovirus retinitis after the initiation of highly active antiretroviral therapy: a 2 year prospective study.
Br J Ophthalmol. 1999 Jun;83(6):652-5. doi: 10.1136/bjo.83.6.652.
7
Training clinicians treating HIV to diagnose cytomegalovirus retinitis.
Bull World Health Organ. 2014 Dec 1;92(12):903-8. doi: 10.2471/BLT.14.142372. Epub 2014 Sep 22.
8
Discontinuation of maintenance therapy in patients with quiescent cytomegalovirus retinitis and elevated CD4+ counts.
Ophthalmology. 1998 Jul;105(7):1259-64. doi: 10.1016/S0161-6420(98)97031-2.
9
Telemedicine screening for cytomegalovirus retinitis at the point of care for human immunodeficiency virus infection.
JAMA Ophthalmol. 2015 Feb;133(2):198-205. doi: 10.1001/jamaophthalmol.2014.4766.
10
Endothelial precipitates and laser flare photometry in patients with acquired immunodeficiency syndrome: a screening test for cytomegalovirus retinitis?
Ger J Ophthalmol. 1996 Nov;5(6):443-8.
引用本文的文献
1
Treating HIV-associated cytomegalovirus retinitis with oral valganciclovir and intra-ocular ganciclovir by primary HIV clinicians in southern Myanmar: a retrospective analysis of routinely collected data.
BMC Infect Dis. 2020 Nov 13;20(1):842. doi: 10.1186/s12879-020-05579-2.
2
Clinical Features of Cytomegalovirus Retinitis in HIV Infected Patients.
Front Cell Infect Microbiol. 2020 Apr 7;10:136. doi: 10.3389/fcimb.2020.00136. eCollection 2020.
本文引用的文献
1
Spectrum of Newly Diagnosed Cytomegalovirus Retinitis in a Developing Country in the HAART Era.
Ocul Immunol Inflamm. 2020;28(1):119-125. doi: 10.1080/09273948.2018.1538460. Epub 2018 Nov 5.
2
Visual acuity outcomes in cytomegalovirus retinitis: early versus late diagnosis.
Br J Ophthalmol. 2018 Dec;102(12):1607-1610. doi: 10.1136/bjophthalmol-2018-312191. Epub 2018 Sep 11.
3
The Enduring Challenge of Advanced HIV Infection.
N Engl J Med. 2017 Jul 20;377(3):283-284. doi: 10.1056/NEJMe1707598.
4
Ocular Manifestations in Patients with Human Immunodeficiency Virus Infection in the Pre-HAART Versus the HAART Era in the North Indian Population.
Ocul Immunol Inflamm. 2017 Jun;25(3):396-404. doi: 10.3109/09273948.2015.1133837. Epub 2016 Feb 24.
5
Distribution and determinants of cytomegalovirus induced end organ disease/s among people living with HIV/AIDS in a poor resource setting: observation from India.
PLoS One. 2015 Feb 13;10(2):e0117466. doi: 10.1371/journal.pone.0117466. eCollection 2015.
6
Training clinicians treating HIV to diagnose cytomegalovirus retinitis.
Bull World Health Organ. 2014 Dec 1;92(12):903-8. doi: 10.2471/BLT.14.142372. Epub 2014 Sep 22.
7
Mortality in patients with AIDS-related cytomegalovirus retinitis in Myanmar.
Clin Infect Dis. 2014 Dec 1;59(11):1650-1. doi: 10.1093/cid/ciu648. Epub 2014 Aug 13.
8
Burden of HIV-related cytomegalovirus retinitis in resource-limited settings: a systematic review.
Clin Infect Dis. 2013 Nov;57(9):1351-61. doi: 10.1093/cid/cit494. Epub 2013 Jul 29.
9
CMV retinitis screening and treatment in a resource-poor setting: three-year experience from a primary care HIV/AIDS programme in Myanmar.
J Int AIDS Soc. 2011 Aug 15;14:41. doi: 10.1186/1758-2652-14-41.
10
Blindness and low vision in a tertiary ophthalmologic center in Thailand: the importance of cytomegalovirus retinitis.
Retina. 2007 Jun;27(5):635-40. doi: 10.1097/01.iae.0000249575.38830.45.
Zotero 插件