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美国四个州通过远程医疗提供药物流产。

Medication Abortion Provided Through Telemedicine in Four U.S. States.

机构信息

Planned Parenthood Federation of America, New York, New York; Ibis Reproductive Health, Cambridge, Massachusetts; and Advancing New Standards in Reproductive Health (ANSIRH), Bixby Center for Global Reproductive Health, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, Oakland, California.

出版信息

Obstet Gynecol. 2019 Aug;134(2):343-350. doi: 10.1097/AOG.0000000000003357.

Abstract

OBJECTIVE

To assess outcomes of medication abortion provided through telemedicine compared with standard medication abortion at Planned Parenthood health centers in four U.S. states.

METHODS

In this retrospective cohort study, we analyzed electronic health records for patients receiving telemedicine compared with standard medication abortion at 26 health centers in Alaska, Idaho, Nevada, and Washington from April 2017 to March 2018. All patients had on-site ultrasound scans, laboratory testing, and counseling and provided informed consent before meeting with the clinician. Telemedicine patients met with a clinician by secure videoconference platform; standard patients met with a clinician in person. We also reviewed adverse event reports submitted during this period. Study outcomes included ongoing pregnancy, receipt of or referral for aspiration procedure, and clinically significant adverse events. To compare outcomes between the telemedicine and standard groups, we performed logistic regression accounting for gestational age and health center clustering.

RESULTS

A total of 5,952 patients underwent medication abortion (738 telemedicine and 5,214 standard). Mean gestational age was 50.4 days for telemedicine patients compared with 48.9 days for standard patients (prevalence ratio 1.02; 95% CI 1.00-1.03). We had outcome data for 4,456 (74.9%) patients; follow-up within 45 days of abortion was lower among telemedicine patients (60.3%) than standard patients (76.9%) (prevalence ratio 0.83; 95% CI 0.78-0.88). Among patients with follow-up data, ongoing pregnancy was less common among telemedicine patients (2/445, 0.5%) than standard patients (71/4,011, 1.8%) (adjusted odds ratio [OR] 0.23; 95% CI 0.14-0.39). Aspiration procedures were less common among telemedicine patients (6/445, 1.4%) than standard patients (182/4,011, 4.5%) (adjusted OR 0.28; 95% CI 0.17-0.46). Fewer than 1% of patients in each group reported clinically significant adverse events. No deaths were reported.

CONCLUSION

Findings from this study conducted across geographically diverse settings support existing evidence that outcomes for medication abortion provided through telemedicine are comparable with standard provision of medication abortion. Differences in observed outcomes may be due to differential follow-up between groups.

摘要

目的

评估美国四个州计划生育协会医疗中心提供的远程医疗药物流产与标准药物流产的结果。

方法

在这项回顾性队列研究中,我们分析了 2017 年 4 月至 2018 年 3 月期间,在阿拉斯加、爱达荷州、内华达州和华盛顿的 26 个医疗中心接受远程医疗和标准药物流产的患者的电子健康记录。所有患者均进行了现场超声扫描、实验室检查和咨询,并在与临床医生会面之前提供了知情同意。远程医疗患者通过安全视频会议平台与临床医生会面;标准患者亲自与临床医生会面。我们还审查了在此期间提交的不良事件报告。研究结果包括持续妊娠、接受或转介抽吸程序以及临床显著不良事件。为了比较远程医疗组和标准组的结果,我们进行了逻辑回归,考虑了妊娠龄和医疗中心聚类。

结果

共有 5952 名患者接受了药物流产(远程医疗 738 例,标准 5214 例)。远程医疗患者的平均妊娠龄为 50.4 天,而标准患者为 48.9 天(流行率比 1.02;95%CI 1.00-1.03)。我们有 4456 名(74.9%)患者的结局数据;流产后 45 天内,远程医疗患者的随访率低于标准患者(60.3%比 76.9%)(流行率比 0.83;95%CI 0.78-0.88)。在有随访数据的患者中,远程医疗患者持续妊娠的比例低于标准患者(2/445,0.5%比 71/4011,1.8%)(调整后的优势比[OR]0.23;95%CI 0.14-0.39)。远程医疗患者抽吸程序的比例低于标准患者(6/445,1.4%比 182/4011,4.5%)(调整后的 OR 0.28;95%CI 0.17-0.46)。每组不到 1%的患者报告了临床显著的不良事件。没有报告死亡。

结论

在地理分布广泛的环境中进行的这项研究结果支持现有证据,即通过远程医疗提供的药物流产结果与标准药物流产提供的结果相当。观察到的结果差异可能是由于两组之间的随访差异。

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