不同种族口腔癌患者的生存率。
Survival of Oral Cancer Patients in Different Ethnicities.
作者信息
Ghani Wan Maria Nabillah, Ramanathan Anand, Prime Stephen Stewart, Yang Yi-Hsin, Razak Ishak Abdul, Abdul Rahman Zainal Ariff, Abraham Mannil Thomas, Mustafa Wan Mahadzir Wan, Tay Keng Kiong, Kallarakkal Thomas George, Doss Jennifer Geraldine, Cheong Sok Ching, Bustam Anita Zarina, Zain Rosnah Binti
机构信息
Faculty of Dentistry, Oral Cancer Research and Coordinating Centre (OCRCC), University of Malaya , Kuala Lumpur , Malaysia.
Department of Oro-Maxillofacial Surgical and Medical Sciences, Faculty of Dentistry, University of Malaya , Kuala Lumpur , Malaysia.
出版信息
Cancer Invest. 2019;37(7):275-287. doi: 10.1080/07357907.2019.1635614. Epub 2019 Jul 15.
Previous studies found that ethnicity influences oral cancer patients' survival; however, most studies were limited to certain ethnic groups particularly from the West, thus of limited relevance to Asians where the disease is most prevalent. We investigated the relationship between ethnicity and patient survival in multi-racial Malaysia. 5-year survival rate was 40.9%. No statistically significant difference was observed in survival between Malays, Chinese, Indians and Indigenous peoples (45.7%, 44.0%, 41.3%, 27.7% respectively). Increased tumor size, lymph node involvement and advanced tumor were predictive of poor survival. We conclude that ethnicity has no effect on survival or its prognostic indicators.
以往研究发现，种族会影响口腔癌患者的生存率；然而，大多数研究仅限于特定种族群体，特别是来自西方的群体，因此与该疾病最为普遍的亚洲人群相关性有限。我们在多民族的马来西亚调查了种族与患者生存率之间的关系。5年生存率为40.9%。马来人、华人、印度人和原住民之间的生存率未观察到统计学上的显著差异（分别为45.7%、44.0%、41.3%、27.7%）。肿瘤大小增加、淋巴结受累和肿瘤进展是生存率低的预测因素。我们得出结论，种族对生存率或其预后指标没有影响。
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