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血管内下腔静脉滤器取出的费用和并发症。

Costs and complications of endovascular inferior vena cava filter retrieval.

机构信息

Section of Vascular Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Conn.

National Public Health Institute of Liberia, Monrovia, Liberia.

出版信息

J Vasc Surg Venous Lymphat Disord. 2019 Sep;7(5):653-659.e1. doi: 10.1016/j.jvsv.2019.02.017. Epub 2019 Jul 12.

DOI:10.1016/j.jvsv.2019.02.017
PMID:31307952
Abstract

OBJECTIVE

Advanced endovascular techniques are frequently used for challenging inferior vena cava (IVC) filter retrieval. However, the costs of IVC filter retrieval have not been studied. This study compares IVC filter retrieval techniques and estimates procedural costs.

METHODS

Consecutive IVC filter retrievals performed at a tertiary center between 2009 and 2014 were retrospectively reviewed. Procedures were classified as standard retrieval (SR) if they required only a vascular sheath and a snare device and as advanced endovascular retrieval (AER) if additional endovascular techniques were used for retrieval. Cost data were based on hospital bills for the procedures. Patients' characteristics, filter dwell time, retrieval procedure details, complications, and costs were compared between the groups. All statistical comparisons were performed using SAS 9.3 software.

RESULTS

There were 191 IVC filter retrievals (SR, 157; AER, 34) in 183 patients (mean age, 55 years; 51% male). Fifteen filters (7.9%) were placed at an outside hospital. The indications for placement were mostly therapeutic (76% vs 24% for prophylaxis). All IVC filters were retrievable, with Bard Eclipse (Bard Peripheral Vascular, Tempe, Ariz; 34%) and Cook Günther Tulip (Cook Medical, Bloomington, Ind; 24%) the most common. Venous ultrasound examination of the lower extremities of 133 patients (70%) was performed before retrieval, whereas only 5 patients (2.6%) received a computed tomography scan of the abdomen. There was no difference in the mean filter dwell time in the two groups (SR, 147.9 ± 146.1 days; AER, 161.4 ± 91.3 days; P = .49). AERs were more likely to have had prior attempts at retrieval (23.5%) compared with SRs (1.9%; P < .001). The most common AER techniques used were the wire loop and snare sling (47.1%) and the stiff wire displacement (44.1%). Bronchoscopy forceps was used in four cases (11.8%); this was the only off-label device used. AERs were more likely to require more than one venous access site for the retrieval procedure (23.5% vs 0%; P < .001). AERs were significantly more likely to have longer fluoroscopy time (34.4 ± 18.3 vs 8.1 ± 7.9 minutes; P < .001) and longer total procedural time (102.8 ± 59.9 vs 41.1 ± 25.0 minutes; P < .001) compared with SRs. The complication rate was higher with AER (20.6%) than with SR (5.2%; P = .006). Most complications were abnormal radiologic findings that did not require additional intervention. The procedural cost of AER was significantly higher (AER, $14,565 ± $6354; SR, $7644 ± $2810; P < .001) than that of SR. This translated to an average increase in cost of $6921 ± $3544 per retrieval procedure for AER.

CONCLUSIONS

Advanced endovascular techniques provide a feasible alternative when standard IVC filter retrieval techniques do not succeed. However, these procedures come with a higher cost and higher rate of complications.

摘要

目的

对于有挑战性的下腔静脉(IVC)滤器取出术,常采用先进的血管内技术。然而,IVC 滤器取出术的成本尚未得到研究。本研究比较了 IVC 滤器取出技术,并对手术成本进行了评估。

方法

回顾性分析 2009 年至 2014 年在一家三级中心进行的连续 IVC 滤器取出术。如果仅需要血管护套和圈套器即可进行的程序被归类为标准取出术(SR),如果需要额外的血管内技术进行取出术,则归类为先进的血管内取出术(AER)。成本数据基于手术的医院账单。比较两组患者的特征、滤器留置时间、取出程序细节、并发症和成本。所有统计比较均使用 SAS 9.3 软件进行。

结果

183 例患者中有 191 例(SR,157 例;AER,34 例)进行了 IVC 滤器取出术(平均年龄 55 岁;51%为男性)。15 个滤器(7.9%)是在其他医院放置的。放置的指征主要是治疗性的(76%与 24%的预防性)。所有 IVC 滤器均可取出,其中 Bard Eclipse(Bard Peripheral Vascular,Tempe,Ariz;34%)和 Cook Günther Tulip(Cook Medical,Bloomington,Ind;24%)最为常见。133 例患者(70%)在取出前进行了下肢静脉超声检查,而仅有 5 例患者(2.6%)接受了腹部 CT 扫描。两组滤器留置时间无差异(SR,147.9 ± 146.1 天;AER,161.4 ± 91.3 天;P =.49)。AER 比 SR 更有可能有过多次尝试取出(23.5%与 1.9%;P <.001)。最常用的 AER 技术是圈套线和圈套索(47.1%)和硬线移位(44.1%)。在 4 例中使用了支气管镜夹(11.8%);这是唯一使用的非标签设备。AER 更有可能需要多个静脉入路来进行取出程序(23.5%与 0%;P <.001)。AER 更有可能需要更长的透视时间(34.4 ± 18.3 与 8.1 ± 7.9 分钟;P <.001)和更长的总手术时间(102.8 ± 59.9 与 41.1 ± 25.0 分钟;P <.001)。与 SR 相比,AER 的并发症发生率更高(20.6%与 5.2%;P =.006)。大多数并发症是不需要额外干预的异常放射学发现。AER 的手术费用明显高于 SR(AER,$14,565 ± $6354;SR,$7644 ± $2810;P <.001)。这意味着 AER 每例手术的成本平均增加了$6921 ± $3544。

结论

当标准的 IVC 滤器取出技术失败时,先进的血管内技术提供了可行的替代方案。然而,这些程序的成本更高,并发症发生率更高。

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