Shah Asim Ali, Jamil Bushra, Naseem Sarah, Khan Abdul Wadood, Ali Yasir, Hussain Khalid, Abbasi Shahid Ahmad
Fauji Foundation Hospital, Rawalpindi, Pakistan.
National University of Medical Sciences (NUMS), Rawalpindi.
J Pak Med Assoc. 2019 Jul;69(7):981-984.
To determine the prevalence of resistant pathogens and their antimicrobial susceptibility pattern in an intensive care unit.
The cross-sectional observational study was conducted at Foundation Hospital, Rawalpindi, Pakistan, from May to September 2016, and comprised tracheal tubes which were collected in sputum culture bottles from patients with clinical findings of ventilator associated pneumonia. The tubes were cultured to locate the resistant pathogens.
A total of 113 different strains of bacteria were isolated from 80 patients. The main isolated bacteria was acinetobacter baumannii 45(39.8%) followed by klebsiella pneumonia 14(12.3%) and methicillin-resistant staphylococcus aureus 13(11.5%). Polymyxin B was the most appropriate drug for treating patients infected with acinetobacter baumannii with a sensitivity of 64% while vancomycin and linez oli dhad 100% sensitivity for methicill in - resistant staphylococcusaureus.
Acinetobacter baumannii was the most prevalent strain in tracheal tubes and polymyxin B was the most effective medicine.
确定重症监护病房耐药病原体的流行情况及其抗菌药敏模式。
2016年5月至9月在巴基斯坦拉瓦尔品第基础医院进行了横断面观察研究，纳入了从有呼吸机相关性肺炎临床表现的患者痰液培养瓶中采集的气管导管。对导管进行培养以找出耐药病原体。
从80例患者中分离出共113种不同的细菌菌株。主要分离出的细菌是鲍曼不动杆菌45株（39.8%），其次是肺炎克雷伯菌14株（12.３%）和耐甲氧西林金黄色葡萄球菌13株（11.5%）。多粘菌素B是治疗鲍曼不动杆菌感染患者的最合适药物，敏感性为64%，而万古霉素和利奈唑胺对耐甲氧西林金黄色葡萄球菌的敏感性为100%。
鲍曼不动杆菌是气管导管中最常见的菌株，多粘菌素B是最有效的药物。
