Uejima Kentaro, Hayasaka Masatoshi, Kato Jitsu, Sakata Wakako, Otsuka Susumu, Watanabe Fumiyuki, Yoshida Yoshikazu, Kamei Miwako
Department of Pharmacy, Nihon University Itabashi Hospital, Tokyo, Japan.
Nihon University School of Pharmacy, Funabashi-shi, Chiba, Japan.
Integr Pharm Res Pract. 2019 Jul 2;8:63-74. doi: 10.2147/IPRP.S197135. eCollection 2019.
Chronic pain is a common symptom that is suffered by 20% of the overall population in Japan. Although pharmacotherapy is critical for the treatment of chronic pain, there are no reports on the pharmacies. In the present study, we examined the effect of hospital-community pharmacy cooperative training on improving drug-taking compliance, pain relief, anxiety, insomnia, and motor function in patients with chronic pain. The subject sample included 87 patients with chronic pain who were examined for the first time at the outpatient services department of Nihon University Itabashi Hospital. Patients were interviewed to obtain information regarding drugs used before and after the treatment, habitually used community pharmacies, presence of cooperative training with Itabashi Hospital, drug-taking compliance, and side effects. We compared treatment outcomes before and after consultation using the Brief Pain Inventory (BPI), Hospital Anxiety and Depression Scale (HADS), EuroQol Group measure (EQ-5D) for quality of life, Athens Insomnia Scale, and Locomo 25 scale for motor function. In patients who used community pharmacies that perform training, drug-taking compliance was significantly better, and a significant improvement was observed in the scores of BPI, HADS Anxiety, Athens Insomnia, and Locomo 25. Pharmacotherapy is essential for the treatment of chronic pain. To this end, appropriate drugs with proper drug management guidance are indispensable. In this study, the use of community pharmacies that have undergone cooperative training with hospitals improves pain and anxiety. This is achieved through proper drug management guidance, shared awareness of drug information, and achievement of better drug-taking compliance. To improve the quality of treatment for chronic pain, involvement of community pharmacies such as by providing accurate information is essential. In the future, expanding cooperative training with hospitals may further help reassure patients, facilitate drug-taking, and improve the quality of treatment for chronic pain.
慢性疼痛是一种常见症状，日本20%的总人口都遭受其困扰。尽管药物治疗对慢性疼痛的治疗至关重要，但关于药房的相关报道却很少。在本研究中，我们考察了医院 - 社区药房合作培训对改善慢性疼痛患者的服药依从性、疼痛缓解、焦虑、失眠和运动功能的效果。研究对象样本包括87名在日本大学板桥医院门诊首次接受检查的慢性疼痛患者。通过访谈患者以获取有关治疗前后使用的药物、习惯使用的社区药房、与板桥医院的合作培训情况、服药依从性及副作用等信息。我们使用简明疼痛量表（BPI）、医院焦虑抑郁量表（HADS）、用于评估生活质量的欧洲五维度健康量表（EQ - 5D）、雅典失眠量表以及用于评估运动功能的Locomo 25量表比较了咨询前后的治疗效果。在使用进行过培训的社区药房的患者中，服药依从性显著更好，并且在BPI、HADS焦虑、雅典失眠和Locomo 25量表的得分上有显著改善。药物治疗对慢性疼痛的治疗至关重要。为此，具备适当药物管理指导的合适药物不可或缺。在本研究中，使用与医院进行过合作培训的社区药房可改善疼痛和焦虑状况。这是通过适当的药物管理指导、药物信息的共享意识以及实现更好的服药依从性来达成的。为提高慢性疼痛的治疗质量，让社区药房参与进来，比如提供准确信息，至关重要。未来，扩大与医院的合作培训可能会进一步帮助患者安心、促进服药并提高慢性疼痛的治疗质量。
