全身X线照射的抗肿瘤作用：X线敏感的抑制性T细胞群体的可能作用。
Antitumor effect of whole-body X-irradiation: possible role of an X-ray-sensitive T suppressor cell population.
作者信息
Hellström I, Hellström K E
出版信息
Transplant Proc. 1979 Mar;11(1):1073-6.
PMID:313092
Abstract
Findings have been presented which support the concept that SBF and suppressor cells can modify immune responses to tumor antigens in vivo, and they indicate that some types of SBF act through a radiosensitive suppressor cell system. We believe that further understanding of the mechanisms involved will provide methods of manipulating the immune response to certain immunogenic tumors and may thereby help in the development of tumor immunotherapy.
摘要
已有研究结果表明，这些结果支持这样一种概念，即特异性阻断因子（SBF）和抑制细胞可在体内改变对肿瘤抗原的免疫反应，并且这些结果表明某些类型的SBF是通过一个对辐射敏感的抑制细胞系统发挥作用的。我们相信，对其中涉及的机制的进一步了解将提供操纵对某些免疫原性肿瘤的免疫反应的方法，从而可能有助于肿瘤免疫疗法的发展。
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