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辐射兴奋效应:好的、坏的和丑的。

Radiation hormesis: the good, the bad, and the ugly.

机构信息

Lawrence, KS, USA.

出版信息

Dose Response. 2006 Sep 27;4(3):169-90. doi: 10.2203/dose-response.06-102.Luckey.

DOI:10.2203/dose-response.06-102.Luckey
PMID:18648595
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2477686/
Abstract

Three aspects of hormesis with low doses of ionizing radiation are presented: the good, the bad, and the ugly. The good is acceptance by France, Japan, and China of the thousands of studies showing stimulation and/or benefit, with no harm, from low dose irradiation. This includes thousands of people who live in good health with high background radiation. The bad is the nonacceptance of radiation hormesis by the U. S. and most other governments; their linear no threshold (LNT) concept promulgates fear of all radiation and produces laws which have no basis in mammalian physiology. The LNT concept leads to poor health, unreasonable medicine and oppressed industries. The ugly is decades of deception by medical and radiation committees which refuse to consider valid evidence of radiation hormesis in cancer, other diseases, and health. Specific examples are provided for the good, the bad, and the ugly in radiation hormesis.

摘要

低剂量电离辐射的三种适应现象

好的方面、坏的方面和丑陋的方面。好的方面是法国、日本和中国接受了数以千计的研究,这些研究表明,低剂量辐照具有刺激和/或益处,而没有任何危害。这包括数以千计生活在高本底辐射环境中健康良好的人。坏的方面是美国和大多数其他政府不接受辐射适应现象;他们的线性无阈(LNT)概念传播对所有辐射的恐惧,并制定了在哺乳动物生理学上没有依据的法律。LNT 概念导致健康状况不佳、不合理的医学和受压迫的产业。丑陋的方面是医学和辐射委员会几十年来的欺骗行为,他们拒绝考虑辐射适应现象在癌症、其他疾病和健康方面的有效证据。本文为辐射适应现象的好的方面、坏的方面和丑陋的方面提供了具体的例子。

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本文引用的文献

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Health Effects of High Radon Environments in Central Europe: Another Test for the LNT Hypothesis?中欧高氡环境对健康的影响:对线性无阈假说的又一次检验?
Nonlinearity Biol Toxicol Med. 2003 Jan;1(1):3-35. doi: 10.1080/15401420390844447.
2
Historical blunders: how toxicology got the dose-response relationship half right.历史错误:毒理学如何在剂量反应关系上只说对了一半。
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Low dose irradiation as a treatment for gingivitis.低剂量辐射作为治疗牙龈炎的一种方法。
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Suppression of thymic lymphoma induction by life-long low-dose-rate irradiation accompanied by immune activation in C57BL/6 mice.在C57BL/6小鼠中,终身低剂量率照射伴随免疫激活对胸腺淋巴瘤诱导的抑制作用。
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Prolongation of life span associated with immunological modification by chronic low-dose-rate irradiation in MRL-lpr/lpr mice.慢性低剂量率照射对MRL-lpr/lpr小鼠进行免疫调节从而延长其寿命。
Radiat Res. 2004 Feb;161(2):168-73. doi: 10.1667/rr3120.
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A systematic overview of radiation therapy effects in non-Hodgkin's lymphoma.非霍奇金淋巴瘤放射治疗效果的系统综述。
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Hormoligosis in pharmacology.药理学中的激素自稳状态
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Radiation-induced versus endogenous DNA damage: possible effect of inducible protective responses in mitigating endogenous damage.辐射诱导的DNA损伤与内源性DNA损伤:诱导性保护反应在减轻内源性损伤中的可能作用。
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Chemical hormesis: its historical foundations as a biological hypothesis.化学兴奋效应:作为一种生物学假说的历史基础
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