Fan Xuanzi, Xiao Pin, Jiao Zeqing, Yang Tingting, Dai Xiaojuan, Xu Wengang, Tan Jin Da, Cui Ganglong, Su Hongmei, Fang Weihai, Wu Jie
Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Republic of Singapore.
College of Chemistry, Beijing Normal University, Beijing, 100875, China.
Angew Chem Int Ed Engl. 2019 Sep 2;58(36):12580-12584. doi: 10.1002/anie.201908556. Epub 2019 Aug 5.
Chlorosilanes are versatile reagents in organic synthesis and material science. A mild pathway is now reported for the quantitative conversion of hydrosilanes to silyl chlorides under visible-light irradiation using neutral eosin Y as a hydrogen-atom-transfer photocatalyst and dichloromethane as a chlorinating agent. Stepwise chlorination of di- and trihydrosilanes was achieved in a highly selective fashion assisted by continuous-flow micro-tubing reactors. The ability to access silyl radicals using photocatalytic Si-H activation promoted by eosin Y offers new perspectives for the synthesis of valuable silicon reagents in a convenient and green manner.
氯硅烷是有机合成和材料科学中用途广泛的试剂。现在报道了一种温和的方法，在可见光照射下，使用中性曙红Y作为氢原子转移光催化剂，二氯甲烷作为氯化剂，将硅烷定量转化为氯硅烷。在连续流动微管反应器的辅助下，以高选择性的方式实现了二氢硅烷和三氢硅烷的逐步氯化。通过曙红Y促进的光催化Si-H活化获得硅自由基的能力，为以方便和绿色的方式合成有价值的硅试剂提供了新的视角。
