被拘留者头发中葡萄糖醛酸乙酯浓度：一项初步研究。
Ethyl Glucuronide Concentration in Hair of Detainees: A Preliminary Study.
作者信息
Pascali Jennifer Paola, Palumbo Diego, Umani Ronchi Federica, Mari Francesco, Fioravanti Alessia, Bertol Elisabetta
机构信息
Forensic Toxicology Unit, Department of Health Science, University of Florence, 50139, Florence, Italy.
Department of SAIMLAL, University of Rome "La Sapienza", 00185, Rome, Italy.
出版信息
J Forensic Sci. 2020 Jan;65(1):189-192. doi: 10.1111/1556-4029.14132. Epub 2019 Jul 16.
Through the measurement of ethyl glucuronide in hair (hETG), it is possible to assess chronic alcohol abuse over time. In this paper, we present a study on hETG in Italian prison inmates. Analyses were performed by LC-MS according to a previously published method. Results were evaluated using the cut-offs established by the Society of Hair Testing. Positives samples (ETG > 30 pg/mg) accounted for 6% of all subjects, with concentrations ranging from 42 pg/mg up to 270 pg/mg, abstinent subjects (ETG < 7 pg/mg) accounted for 88%, and moderate alcohol consumption (7 < ETG < 30 pg/mg) for 6% of the subjects. No females displayed ETG values above 30 pg/mg. Among positive samples, only two subjects did not declare heavy alcohol consumption and were found strongly positive at 210 and 270 pg/mg. To the best of our knowledge, this represents the first study on ETG hair concentration on prison inmates.
通过测量头发中的乙基葡萄糖醛酸（hETG），可以长期评估慢性酒精滥用情况。在本文中，我们展示了一项针对意大利监狱囚犯hETG的研究。分析采用液相色谱 - 质谱联用仪（LC-MS），依照先前发表的方法进行。结果依据毛发检测协会设定的临界值进行评估。阳性样本（ETG > 30 pg/mg）占所有受试者的6%，浓度范围为42 pg/mg至270 pg/mg，戒酒者样本（ETG < 7 pg/mg）占88%，适度饮酒者样本（7 < ETG < 30 pg/mg）占受试者的6%。没有女性的ETG值高于30 pg/mg。在阳性样本中，只有两名受试者未宣称大量饮酒，但检测发现其ETG值分别高达210 pg/mg和270 pg/mg，呈强阳性。据我们所知，这是第一项关于监狱囚犯头发中ETG浓度的研究。
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