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大鼠脑中UDP半乳糖:神经酰胺半乳糖基转移酶活性的区域及发育评估

Regional and developmental estimations of UDP galactose: ceramide galactosyltransferase activity in the rat brain.

作者信息

Monge M, Zalc B, Kanfer J

机构信息

Unité de Neurobiologie Cellulaire, INSERM U 134, Hôpital de la Salpêtrière, Paris, France.

出版信息

Dev Neurosci. 1988;10(1):43-6. doi: 10.1159/000111954.

DOI:10.1159/000111954
PMID:3131098
Abstract

The activity of the UDP galactose:ceramide galactosyltransferase (C GalT) was determined during development in the mesencephalon, cerebellum, diencephalon, cerebral hemisphere and olfactory bulb of the rat brain. The level of C GalT activity remained fairly constant at a low level until postnatal day 7 (P7), followed by a simultaneous dramatic increase in all regions (with the exception of the olfactory bulb) tested between P15 and P18, and then by a region-specific rate of decline.

摘要

在大鼠脑的中脑、小脑、间脑、大脑半球和嗅球发育过程中,测定了UDP半乳糖:神经酰胺半乳糖基转移酶(C GalT)的活性。C GalT活性水平在出生后第7天(P7)之前一直保持在较低水平且相当稳定,随后在P15至P18期间所测试的所有区域(嗅球除外)同时急剧增加,然后以区域特异性速率下降。

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