Masenga Sepiso K, Hamooya Benson M, Nzala Selestine, Kwenda Geoffrey, Heimburger Douglas C, Mutale Wilbroad, Koethe John R, Kirabo Annet, Munsaka Sody M
School of Medicine and Health Sciences, Mulungushi University, Livingstone, Zambia.
Department of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka, Zambia.
BMC Res Notes. 2019 Jul 16;12(1):424. doi: 10.1186/s13104-019-4470-2.
The objective of this study is to quantify and compare the effect of excess dietary salt on immune cell activation and blood pressure in HIV versus HIV negative individuals.
Salt-sensitivity is associated with increased immune cell activation in animal studies. This concept has not been tested in people living with HIV. This study will therefore add more information in elucidating the interaction between HIV infection and/or anti-retroviral therapy (ART), immune-activation/inflammation and hypertension.
本研究的目的是量化并比较过量饮食盐分对HIV感染者与HIV阴性个体免疫细胞激活及血压的影响。
在动物研究中，盐敏感性与免疫细胞激活增加有关。这一概念尚未在HIV感染者中进行过测试。因此，本研究将为阐明HIV感染和/或抗逆转录病毒疗法（ART）、免疫激活/炎症与高血压之间的相互作用提供更多信息。
