Department of Family Practice, Faculty of Medicine of Saint-Etienne, University of Lyon, France.
Department of Family Practice, Faculty of Medicine of Saint-Etienne, University of Lyon, France.
Vaccine. 2019 Aug 14;37(35):4864-4866. doi: 10.1016/j.vaccine.2019.07.025. Epub 2019 Jul 13.
A 57-year-old female experienced two successive peripheral facial paralysis (PFP) episodes following influenza immunization in 2009 and 2016 with two different vaccines. The similarity of chronology and semiology between the two events and the absence of alternative etiology plead for intrinsic accountability. Extrinsic accountability relies on previous case reports of PFP related to flu vaccination (26 cases in the French pharmacovigilance database and 4 cases in the medical literature).
一位 57 岁女性于 2009 年和 2016 年先后两次在流感疫苗接种后出现周围性面瘫(PFP),两次均为不同疫苗。两次事件的时间和症状相似,且无其他病因,提示可能为内在关联性。外在关联性取决于之前与流感疫苗接种相关的 PFP 病例报告(法国药物警戒数据库中 26 例,医学文献中 4 例)。