Ostrowski Rochella A, Metgud Sheela, Tehrani Rodney, Jay Walter M
Division of Allergy, Immunology, and Rheumatology, Department of Medicine, Loyola, University Chicago, Stritch School of Medicine, Maywood, Illinois, USA.
Department of Ophthalmology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois, USA.
Neuroophthalmology. 2019 Jul 2;43(3):159-170. doi: 10.1080/01658107.2019.1604763. eCollection 2019 Jun.
In recent years, the search for the cause of giant cell arteritis (GCA) has led investigators to look to varicella zoster virus (VZV) as the answer. In some ways, the nature of VZV infection makes it an attractive explanation for the pathology observed in GCA. However, studies to date yield a level of inconsistency that still leaves uncertainty as to whether VZV directly causes GCA, and positive findings have not been successfully reproduced.
近年来，对巨细胞动脉炎（GCA）病因的探寻促使研究人员将目光投向水痘带状疱疹病毒（VZV），认为它是病因所在。在某些方面，VZV感染的特性使其成为GCA中所观察到病理现象的一个有吸引力的解释。然而，迄今为止的研究结果存在一定程度的不一致性，对于VZV是否直接导致GCA仍存在不确定性，且阳性研究结果尚未得到成功重现。
