Mirzai Saeid, Rifai Ahmad Oussama, Webb Shana, Rifai Kareem, Reiner Amanda
OMS III, Alabama College of Osteopathic Medicine, ACOM, 445 Health Sciences Blvd, Dothan, AL, 36303, USA.
The Virtual Nephrologist, INC., PO Box 1750, Lynn Haven, FL, 32444, USA.
IDCases. 2019 Jun 25;17:e00581. doi: 10.1016/j.idcr.2019.e00581. eCollection 2019.
encephalitis is a rare cause of spontaneous, non-traumatic pneumocephalus. Systemic infections with this organism have a fulminant course, likely leading to death within 48 hours, and are commonly associated with hematological or colonic malignancies. The effectiveness of an antibacterial regimen is unknown because of a lack of studies. The best prognosis is observed in patients undergoing early surgical intervention for localized intracranial processes. Here we describe a case of rapidly developing sepsis as a result of bacteremia and hematogenous spread, resulting in encephalitis and pneumocephalus in a patient without a diagnosed malignancy. The patient presented to the emergency department with diabetic ketoacidosis, which led to the diagnosis of new-onset type 1 diabetes mellitus. There are currently 19 reported cases of central nervous system infections in the literature, with 12 of them having pneumocephalus. Natural remedies, such as drinking kombucha tea and performing coffee enemas, that were used by our patient may have played a role in the dissemination of . In survivors of this fulminant illness, colonic and hematologic malignancies should be excluded because of their association with such infections. Type 1 diabetes mellitus, drinking kombucha tea, and performing coffee enemas may be newly recognized risk factors associated with the dissemination of .
脑炎是自发性、非创伤性气颅的罕见病因。该病原体引起的全身感染病程凶险，可能在48小时内导致死亡，且通常与血液系统或结肠恶性肿瘤相关。由于缺乏研究，抗菌治疗方案的有效性尚不清楚。对于局限性颅内病变早期接受手术干预的患者，预后最佳。在此，我们描述一例因菌血症和血行播散导致迅速发展的脓毒症病例，该病例在一名未诊断出恶性肿瘤的患者中引发了脑炎和气颅。患者因糖尿病酮症酸中毒就诊于急诊科，进而诊断为新发1型糖尿病。目前文献报道有19例中枢神经系统感染病例，其中12例伴有气颅。我们的患者所使用的天然疗法，如饮用康普茶和进行咖啡灌肠，可能在病原体传播中起了作用。在这种暴发性疾病的幸存者中，应排除结肠和血液系统恶性肿瘤，因为它们与此类感染有关。1型糖尿病、饮用康普茶和进行咖啡灌肠可能是与病原体传播相关的新发现危险因素。
