曼氏血吸虫病神经型实验模型中眼部受累情况的特征描述。
Characterisation of ocular involvement in an experimental model of neuroschistosomiasis mansoni.
作者信息
Fidelis Thiago Andre Alves, Brasileiro-Filho Geraldo, Santos Helena Hollanda, Vasconcelos-Santos Daniel Vitor, Parreiras Patricia M, Coelho Paulo Marcos Z, Araujo Neusa, Chaud Marco Vinicius, Lambertucci José Roberto
机构信息
Universidade Federal de Minas Gerais, Faculdade de Medicina, Departamento de Doenças Infectoparasitárias, Belo Horizonte, MG, Brasil.
Universidade de Sorocaba, Laboratório de Biomateriais e Nanotecnologia, Sorocaba, SP, Brasil.
出版信息
Mem Inst Oswaldo Cruz. 2019;114:e190029. doi: 10.1590/0074-02760190029. Epub 2019 Jul 15.
The Global Burden of Disease Study 2010 listed schistosomiasis among the leading 100 causes of death in Brazil, responsible for 3.6% of the estimated total of deaths globally. Eye and adnexa are very rarely affected by schistosomiasis mansoni, with limited documentation of ocular pathology in this setting. This short communication reports ocular histolopathological findings in a murine model of neuroschistosomiasis mansoni. Lesions were found in the bulbar conjunctiva, lacrimal gland, choroid and corneoscleral limbus.
《2010年全球疾病负担研究》将血吸虫病列为巴西主要的100种死因之一，占全球估计死亡总数的3.6%。曼氏血吸虫病极少累及眼及附属器，关于这种情况下眼部病理学的文献记载有限。本简短通讯报道了曼氏神经血吸虫病小鼠模型中的眼部组织病理学发现。在球结膜、泪腺、脉络膜和角膜巩膜缘发现了病变。
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