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儿童期曼氏血吸虫性神经血吸虫病:一种未被诊断的病理情况?

Mansonic neuroschistosomiasis in the childhood: an undiagnosed pathology?

作者信息

Dastoli Patricia Alessandra, da Costa Marcos Devanir Silva, Nicácio Jardel Mendonça, Pinho Ricardo Silva, Ferrarini Maria Aparecida Gadiani, Cavalheiro Sergio

机构信息

Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, 720, 6th floor, Sao Paulo, Brazil.

Department of Pediatrics, Rua Napoleão de Barros, 720, 9th floor, Sao Paulo, Brazil.

出版信息

Childs Nerv Syst. 2023 Feb;39(2):481-489. doi: 10.1007/s00381-022-05696-0. Epub 2022 Oct 18.

Abstract

Schistosomiasis is an endemic parasitic disease in several tropical countries. In Brazil, the only prevalent species of parasite responsible for schistosomiasis is Schistosoma mansoni. Neuroschistosomiasis is the second most frequent form of infection and the primary ectopic manifestation, with predominant involvement of the lower thoracic spinal cord and lumbar and lumbosacral regions. The frequent contact of children with contaminated ponds and the immaturity of their immune systems make this age group especially susceptible to infection by this parasite. Therefore, neuroschistosomiasis mansoni should always be considered in cases of transverse myelitis in children from endemic regions. The treatment for this condition is quite simple and effective, resulting in total recovery of neurological deficits if the diagnosis is made early.

摘要

血吸虫病是几种热带国家的地方性寄生虫病。在巴西,导致血吸虫病的唯一流行寄生虫种类是曼氏血吸虫。神经血吸虫病是第二常见的感染形式和主要的异位表现,主要累及下胸段脊髓以及腰段和腰骶部区域。儿童经常接触受污染的池塘以及其免疫系统不成熟,使得这个年龄组特别容易受到这种寄生虫的感染。因此,对于来自流行地区的儿童发生横贯性脊髓炎的病例,应始终考虑曼氏神经血吸虫病。这种疾病的治疗相当简单且有效,如果早期诊断,神经功能缺损可完全恢复。

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