Departamento de Doenças Infectoparasitárias/Departamento de Anatomia Patológica e Medicina Legal, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Laboratório de Esquistossomose, Instituto René Rachou, Fundação Oswaldo Cruz-Fiocruz, Belo Horizonte, MG, Brazil.
Mem Inst Oswaldo Cruz. 2020;115:e190383. doi: 10.1590/0074-02760190383. Epub 2020 May 11.
Schistosomiasis mansoni presents many clinical manifestations during migration of schistosomes in their hosts, including diarrhea, hepatomegaly, splenomegaly, liver abscesses, skinlesions, brain tumors and myeloradiculopathy. No lesions have been reported in skeletal striated muscles due to schistosomiasis mansoni in the literature. This short communication reports the histopathological findings on skeletal musculature in a murine model of neuroeschistosomiasis mansoni. Lesions were found in the tongue, masseter muscle, buccinator muscle, digastric muscle and temporalis muscle. Worm recovery was carried out to confirm the infection. We describe here, for the first time in the literature, injuries in the skeletal musculature due to Schistosoma mansoni nfection.
曼氏血吸虫病在血吸虫在宿主体内迁移过程中表现出许多临床表现，包括腹泻、肝肿大、脾肿大、肝脓肿、皮肤损伤、脑肿瘤和骨髓神经根病。文献中没有报道由于曼氏血吸虫病导致骨骼肌出现病变。本短篇通讯报告了神经曼氏血吸虫病小鼠模型中骨骼肌的组织病理学发现。在舌、咬肌、颊肌、二腹肌和颞肌中发现了病变。进行了蠕虫回收以确认感染。我们在这里首次描述了曼氏血吸虫感染引起的骨骼肌损伤。
