并非所有淋巴结都一样。

Not All Lymph Nodes Are Created Equal.

机构信息

Department of Physiology and Pharmacology, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

出版信息

Immunity. 2019 Jul 16;51(1):12-14. doi: 10.1016/j.immuni.2019.06.018.

DOI:10.1016/j.immuni.2019.06.018

PMID:31315030

Abstract

Appropriate priming of tolerogenic or effector immune responses is crucial for intestinal homeostasis. Recently in Nature, Esterházy et al. (2019) reveal how compartmentalization of lymphatic drainage to functionally distinct lymph nodes facilitates the simultaneous induction of tolerogenic and effector responses.

摘要

适当诱导耐受原性或效应免疫应答对于肠道稳态至关重要。近期在《自然》杂志上，Esterházy 等人（2019 年）揭示了淋巴管引流到功能不同的淋巴结的分隔如何促进同时诱导耐受原性和效应应答。