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内耳出血相关性突发性聋及眩晕的临床研究

[Clinical study of inner ear hemorrhage-associated sudden deafness and vertigo].

作者信息

Chen K T, Zhuang H W, Wu X, Liu M, Xiong G X

机构信息

Department of Otorhinolaryngology, the First Affiliated Hospital, Sun Yat-sen University and Institute of Otorhinolaryngology, Sun Yat-sen University, Guangzhou 510080, China.

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Jul 7;54(7):495-500. doi: 10.3760/cma.j.issn.1673-0860.2019.07.003.

Abstract

To analyze the clinical features and possible pathogenesis of sudden deafenss and vertigo induced by inner ear hemorrhage. Clinical data of 30 patients with inner ear hemorrhage, from the first affiliated hospital of Sun Yat-sen university during Jan 2016 to May 2017, were retrospectively analyzed. Vergito and profound deafness were seen in all patients. The duration of vertigo ranged from 24 hours to three days in 11 cases, three to 14 days in the remaining 19 cases. Simultaneous occurrence of vergito and deafenss were seen in 24 patients. Semicircular canal hypofunction and abnormal cervical vestibular evoked myogenic potentials(C-VEMP)/ocular vestibular evoked myogenic potentials(O-VEMP) were detected in all cases. Ten patients had benign paroxysmal positional vertigo(BPPV) simultaneously. Hearing recovered in 20% of the cohort posttreatment. Dizziness and balance disturbance disappeared 1 to 2 months after therapy in 16 cases. Long term (6 months) follow up revealed poor hearing outcome and vestibular rehabilitation. Vestibular vertigo and profound sensorineural hearing loss, with unsatisfactory clinical prognosis, constituted the characters of inner ear hemorrhage-associated sudden deafness.

摘要

分析内耳出血所致突发性聋伴眩晕的临床特征及可能的发病机制。回顾性分析2016年1月至2017年5月中山大学附属第一医院收治的30例内耳出血患者的临床资料。所有患者均出现眩晕和重度聋。11例患者眩晕持续时间为24小时至3天,其余19例为3至14天。24例患者眩晕和耳聋同时出现。所有病例均检测到半规管功能减退及异常的颈前庭诱发肌源性电位(C-VEMP)/眼前庭诱发肌源性电位(O-VEMP)。10例患者同时合并良性阵发性位置性眩晕(BPPV)。治疗后20%的患者听力恢复。16例患者治疗后1至2个月头晕及平衡障碍消失。长期(6个月)随访显示听力预后及前庭康复效果不佳。前庭性眩晕和重度感音神经性听力损失,临床预后不理想,构成内耳出血相关突发性聋的特点。

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